Y443_MYCPN
ID Y443_MYCPN Reviewed; 409 AA.
AC P75335;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Probable ATP-dependent RNA helicase MG308 homolog;
DE EC=3.6.4.13;
GN OrderedLocusNames=MPN_443; ORFNames=H08_orf409, MP398;
OS Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS pneumoniae).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=272634;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29342 / M129;
RX PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT pneumoniae.";
RL Nucleic Acids Res. 24:4420-4449(1996).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. {ECO:0000305}.
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DR EMBL; U00089; AAB96046.1; -; Genomic_DNA.
DR PIR; S73724; S73724.
DR RefSeq; NP_110131.1; NC_000912.1.
DR RefSeq; WP_010874799.1; NC_000912.1.
DR AlphaFoldDB; P75335; -.
DR SMR; P75335; -.
DR IntAct; P75335; 1.
DR STRING; 272634.MPN_443; -.
DR EnsemblBacteria; AAB96046; AAB96046; MPN_443.
DR KEGG; mpn:MPN_443; -.
DR PATRIC; fig|272634.6.peg.479; -.
DR HOGENOM; CLU_003041_1_3_14; -.
DR OMA; EYCTPIQ; -.
DR BioCyc; MPNE272634:G1GJ3-713-MON; -.
DR Proteomes; UP000000808; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome;
KW RNA-binding.
FT CHAIN 1..409
FT /note="Probable ATP-dependent RNA helicase MG308 homolog"
FT /id="PRO_0000055113"
FT DOMAIN 26..179
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 190..349
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT MOTIF 126..129
FT /note="DEVD box"
FT BINDING 39..46
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ SEQUENCE 409 AA; 47001 MW; 02AC88B04F93A07C CRC64;
MHFIQPLQAF LQTKHIVEFS SIQQAVFKVW PRQNVVGIAE TGSGKTFAYL LPALNQIDVT
LNKPQAVVFV PTKELKWQIL TILNDIKASF TGLKVSENFN SNAHLIVSLI GKDIILHETI
KYVVFDEVDM FLEDSSQAEW INCVQLFQKH KPHFGFFSAT LFNEQLQQIR KQVAPLTVVN
QKKRAWKHSL VKHFLLNLNG QEPFAGLLAL LNYHHNEQVL VFCSNAKSLK QLTSLLAHNQ
LSFKSLHGQL TPNERKHIFT SAANNTVRVL VVSDLLARGI DLPHFSVVIS WDLPLVDSFY
IHRSGRVARF NSWGNSYVFD LPHNQHKLTK FAHKGILFNS VHLERDGTLK FPQLKQSKQK
PAVSSELKTA IKRIKAGYKK VKPNYKKRQK QQIAELFAKR KQRRSWKNF
