ID   Y443_STAAR              Reviewed;         266 AA.
AC   Q6GJN0;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Uncharacterized lipoprotein SAR0443;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAR0443;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; BX571856; CAG39463.1; -; Genomic_DNA.
DR   RefSeq; WP_001269822.1; NC_002952.2.
DR   AlphaFoldDB; Q6GJN0; -.
DR   SMR; Q6GJN0; -.
DR   KEGG; sar:SAR0443; -.
DR   HOGENOM; CLU_071589_0_1_9; -.
DR   OMA; IWTIYTD; -.
DR   OrthoDB; 2108348at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..266
FT                   /note="Uncharacterized lipoprotein SAR0443"
FT                   /id="PRO_0000282157"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   266 AA;  30896 MW;  AC8D839ADA74A65B CRC64;
     MRYLNRVVLY IIVMVLSVFI IGCDKSSDTS EKPKEDSKEA QIKKSFEKTL DMYPIKNLED
     LYDKEGSRDG EFKKGDKGMW TIYTDFAKSN KQGGLSNEGM VLYLDRNTRT AKGHYFVKTF
     YEKDKFPDRK KYKVEMKNNK IILLDKVEDP KLKKRIENFK FFGQYANLKE LKNYNNGDVS
     INENVPSYDA KFKMSNKDEN VKQLRSRYNI PTDKAPVLKM HIDGNLKGSS VGYKKLEIDF
     SKGEKSDLSV IDSLNFQPAK VNEDDE