ID   Y4441_MYCA1             Reviewed;         314 AA.
AC   A0QKY8;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4441;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4441;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68846.1; -; Genomic_DNA.
DR   RefSeq; WP_011726069.1; NC_008595.1.
DR   AlphaFoldDB; A0QKY8; -.
DR   SMR; A0QKY8; -.
DR   EnsemblBacteria; ABK68846; ABK68846; MAV_4441.
DR   KEGG; mav:MAV_4441; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; RMADNMA; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..314
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4441"
FT                   /id="PRO_0000361108"
FT   BINDING         138
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         167..168
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   314 AA;  33875 MW;  37D512FDEE0AE679 CRC64;
     MTSTRYEGDT WDLASSVGVT ATMVAAARAM ATRADNPLIN DPFAEPLVKA VGVDLLSRLA
     GGELDPAELN DVHDGAAGSA GAMSRMADNM AVRTKFFDEF FLNATKAGIA QVVILASGLD
     ARAYRLAWPA GTVVYEVDQP QVIDFKTTAL AQLGAAPTAE RRVVAVDLRD DWPAALRAAG
     FDPTRPTAWS AEGLLGYLPP EAQDRLLDTI TELSAPGSRL ATESAPNPAP GEEEKLKERM
     QAISQRWRAH GFDLDMAGLV YFGERNEAAP YLAGHGWRLN SVTIRDLFAA NGLDPLDDDD
     TRMGEMLYTW GIYE