ID   Y4442_MYCA1             Reviewed;         306 AA.
AC   A0QKY9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4442;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4442;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68338.1; -; Genomic_DNA.
DR   RefSeq; WP_009979053.1; NC_008595.1.
DR   AlphaFoldDB; A0QKY9; -.
DR   SMR; A0QKY9; -.
DR   EnsemblBacteria; ABK68338; ABK68338; MAV_4442.
DR   KEGG; mav:MAV_4442; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; TEHVPDP; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..306
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4442"
FT                   /id="PRO_0000361109"
FT   BINDING         129
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         158..159
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   306 AA;  33612 MW;  D873DBE98A1CBE51 CRC64;
     MSEGRTDGDT WGPAQSVGAT ATMVAAARAV ASQGPDALLD DPLAEPLVRA VGLDPFIRIV
     DGKLDFPDDP LFNRRARAEQ ITVRTRFFDD FFIDATEGGL RQAVILASGL DTRAYRLAWP
     AGTVVYEIDQ PQVIAFKTDT LANLGAAPTA ERRTISIDLR DDWPAALREG GFDVTRPTAW
     SAEGLLPYLP PEAQDRLFDN ITALSAPGSR LATEHVPDPN AFSDERLARI SERWQRLGLN
     LNAADLFYRG ERNVVADYLT GKGWRVTPHP ARQLYARNGF EFPEDEMRAT FGEMSYVDAT
     LTGGRG