ID   Y4444_MYCA1             Reviewed;         304 AA.
AC   A0QKZ0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4444;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4444;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK66429.1; -; Genomic_DNA.
DR   RefSeq; WP_011726070.1; NC_008595.1.
DR   AlphaFoldDB; A0QKZ0; -.
DR   SMR; A0QKZ0; -.
DR   EnsemblBacteria; ABK66429; ABK66429; MAV_4444.
DR   KEGG; mav:MAV_4444; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; FFIKMMD; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..304
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4444"
FT                   /id="PRO_0000361110"
FT   BINDING         130
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         159..160
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   304 AA;  33137 MW;  F98283F2BA25981D CRC64;
     MTRTHDDEWD LASSVGATAT MVAAGRAMAT KDPRGLIDDP FAEPLVRAVG VDFFTKMMDG
     ELDLDAIENA TPVRIQSMVD GMAVRTKYFD DYFVDATDAG VRQVVILASG LDSRAYRLPW
     PAGTVVYEID QPRVIEFKSN TLAEVGAEPT ATRRTIPIDL RGDWPAALSA AGFDPAAPTA
     WLAEGLLIYL PPEAQDRLFD NITALSAPGS TIATEFVPGI VDFDAERVRE MSGSFREHGV
     DIDMASLVYA GERNHVIDYL NGLGWRAEGV TRTELFHRHG IEVPAPEHDD PLGEIIFISA
     TRTG