Y4449_ARATH
ID Y4449_ARATH Reviewed; 386 AA.
AC O23305;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=FHA domain-containing protein At4g14490;
GN OrderedLocusNames=At4g14490; ORFNames=dl3285c;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP STRUCTURE BY NMR OF 1-105.
RG RIKEN structural genomics initiative (RSGI);
RT "Solution structure of the FHA domain of Arabidopsis thaliana hypothetical
RT protein.";
RL Submitted (JAN-2004) to the PDB data bank.
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DR EMBL; Z97336; CAB10228.1; -; Genomic_DNA.
DR EMBL; AL161539; CAB78491.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE83450.1; -; Genomic_DNA.
DR EMBL; AY099748; AAM20599.1; -; mRNA.
DR EMBL; AY128865; AAM91265.1; -; mRNA.
DR PIR; B71407; B71407.
DR RefSeq; NP_193185.1; NM_117529.3.
DR PDB; 1UHT; NMR; -; A=1-105.
DR PDBsum; 1UHT; -.
DR AlphaFoldDB; O23305; -.
DR BMRB; O23305; -.
DR SMR; O23305; -.
DR BioGRID; 12393; 2.
DR IntAct; O23305; 2.
DR STRING; 3702.AT4G14490.1; -.
DR PaxDb; O23305; -.
DR PRIDE; O23305; -.
DR EnsemblPlants; AT4G14490.1; AT4G14490.1; AT4G14490.
DR GeneID; 827096; -.
DR Gramene; AT4G14490.1; AT4G14490.1; AT4G14490.
DR KEGG; ath:AT4G14490; -.
DR Araport; AT4G14490; -.
DR TAIR; locus:2129785; AT4G14490.
DR eggNOG; ENOG502SF2R; Eukaryota.
DR HOGENOM; CLU_041860_0_0_1; -.
DR InParanoid; O23305; -.
DR OMA; FSFLEGH; -.
DR OrthoDB; 1009659at2759; -.
DR PhylomeDB; O23305; -.
DR EvolutionaryTrace; O23305; -.
DR PRO; PR:O23305; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O23305; baseline and differential.
DR Genevisible; O23305; AT.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR CDD; cd00060; FHA; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SSF49879; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..386
FT /note="FHA domain-containing protein At4g14490"
FT /id="PRO_0000220609"
FT DOMAIN 28..78
FT /note="FHA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00086"
FT REGION 286..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 5..13
FT /evidence="ECO:0007829|PDB:1UHT"
FT TURN 14..17
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 28..34
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 38..40
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 43..46
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 51..55
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 57..63
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 72..77
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 83..85
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 90..94
FT /evidence="ECO:0007829|PDB:1UHT"
FT TURN 95..97
FT /evidence="ECO:0007829|PDB:1UHT"
FT STRAND 98..105
FT /evidence="ECO:0007829|PDB:1UHT"
SQ SEQUENCE 386 AA; 43367 MW; C4E4D100CE1A23CF CRC64;
MVTPSLRLVF VKGPREGDAL DYKPGSTIRV GRIVRGNEIA IKDAGISTKH LRIESDSGNW
VIQDLGSSNG TLLNSNALDP ETSVNLGDGD VIKLGEYTSI LVNFVIDDFQ EKKLTRNNRR
QANARKRIRV LESINLGDIT EEEKGLDVKF ENKPSSRVRK VRKIEDSEKL GITDGLQEDL
VEKNGSFRNV ESIQSSSVNL IKVEMEDCAM VEENLGRGLK KRVSSKATRS KKIEESVGKA
CLGVVNVEKV ETLKEKRITR ATRSKKIDIV GDSYLELDMV LNRARKNKGK NKKADQKPLK
SFENDEVTDS GEQGLSCHVE EDMNNELDTD LRKMTLGALF SFLEGHLSKE IIHKTENMIE
PMRSKTQRVR EYISDQRKVQ AKACMC
