ID   Y445_STAAR              Reviewed;         272 AA.
AC   Q6GJM8;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Uncharacterized lipoprotein SAR0445;
DE   Flags: Precursor;
GN   OrderedLocusNames=SAR0445;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAG39465.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BX571856; CAG39465.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000455735.1; NC_002952.2.
DR   AlphaFoldDB; Q6GJM8; -.
DR   SMR; Q6GJM8; -.
DR   KEGG; sar:SAR0445; -.
DR   HOGENOM; CLU_071589_0_1_9; -.
DR   OMA; YSAEYKI; -.
DR   OrthoDB; 1629654at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..272
FT                   /note="Uncharacterized lipoprotein SAR0445"
FT                   /id="PRO_0000282158"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   272 AA;  31660 MW;  F59D60EC0E8777C3 CRC64;
     MEYIKKIALY MSVLLLIIFI GGCGNMKDEQ KKEEQTNKTD SKEEQIKKSF AKTLDMYPIK
     NLEDLYDKEG YRDGEFEKGD KGMWVLYSSI VSEFKGESLK SRGMILKLDR NKRTAKGSYI
     IRELKEDKNH DVQKNEKKYP VKLVNNKIIP TEDVKNEDLK REIENFKLFS QYGEFKSLNT
     DRITNISYNP NAPNYSAEYK INDDDNNIKQ LKNRFNIKSN KNPKLLFKGA GNIKGSSVGY
     KEIQIIFNRN KEESVSCIDS IEFKPSEGDY NE