ID   Y446_CLOAB              Reviewed;         206 AA.
AC   Q97LV8;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Uncharacterized Nudix hydrolase CA_C0446;
DE            EC=3.6.-.-;
GN   OrderedLocusNames=CA_C0446;
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA   Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR   EMBL; AE001437; AAK78426.1; -; Genomic_DNA.
DR   PIR; G96954; G96954.
DR   RefSeq; NP_347086.1; NC_003030.1.
DR   RefSeq; WP_010963768.1; NC_003030.1.
DR   AlphaFoldDB; Q97LV8; -.
DR   SMR; Q97LV8; -.
DR   STRING; 272562.CA_C0446; -.
DR   EnsemblBacteria; AAK78426; AAK78426; CA_C0446.
DR   GeneID; 44996955; -.
DR   KEGG; cac:CA_C0446; -.
DR   PATRIC; fig|272562.8.peg.644; -.
DR   eggNOG; COG1443; Bacteria.
DR   HOGENOM; CLU_060552_1_0_9; -.
DR   OMA; YEFVIEQ; -.
DR   OrthoDB; 1345242at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..206
FT                   /note="Uncharacterized Nudix hydrolase CA_C0446"
FT                   /id="PRO_0000057075"
FT   DOMAIN          29..169
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           69..90
FT                   /note="Nudix box"
FT   BINDING         84
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         88
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   206 AA;  24276 MW;  A27A7CEB99B2F6A3 CRC64;
     MEEEFLDIFD EEERLIGRKS RKEVHEKGYW HSTFHCWVVK REGKKTFLIF QKRHPLKDTA
     PNMFDVSSAG HIKSGESIED GVRELKEELG IDAKPNELIN IGIIKEEFHI GKNIDREFCH
     IYIYSNKAEI ESYTLQRDEV VGLVKIEIDE LARFLDNKID GVFAEGFIVN QEGRRYKLSK
     ILNKDDFVPH KYGYYKIVLR ALMDDY