ID   Y447_MYCGE              Reviewed;         547 AA.
AC   P47685;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Uncharacterized protein MG447;
GN   OrderedLocusNames=MG447;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 107-215.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L43967; AAC72467.1; -; Genomic_DNA.
DR   EMBL; U01788; AAD10610.1; -; Genomic_DNA.
DR   PIR; D64249; D64249.
DR   RefSeq; WP_010869486.1; NC_000908.2.
DR   AlphaFoldDB; P47685; -.
DR   SMR; P47685; -.
DR   STRING; 243273.MG_447; -.
DR   EnsemblBacteria; AAC72467; AAC72467; MG_447.
DR   KEGG; mge:MG_447; -.
DR   eggNOG; COG0534; Bacteria.
DR   HOGENOM; CLU_468356_0_0_14; -.
DR   OMA; VGNWIGS; -.
DR   OrthoDB; 1105799at2; -.
DR   BioCyc; MGEN243273:G1GJ2-540-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002528; MATE_fam.
DR   Pfam; PF01554; MatE; 2.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..547
FT                   /note="Uncharacterized protein MG447"
FT                   /id="PRO_0000210618"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        470..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        499..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   547 AA;  62053 MW;  E6D115C419A2E81B CRC64;
     MNSKRDRFEK QLLIKNVFES KQLFLTILRF TVPTFFFALF SAAYVFIDQI MVIKFVPRSE
     LNPDSIFTDQ SLIDEFKNSA FYKSDSFLSS GLNIKQFIKT VLNISQPLIV LLNAINIFIP
     LGTGVIFSKA IGRNDQNKIQ EAWNTGLIST TVFGLITQFL VLSFAKEWLH YNLDQSSFEQ
     NFQANSFQQF FNKKAIDVAS EYVYILIGLN IIPMLSRLFF YLAQSEGRQL FIAIVPPIAN
     LINILIVFLL VRYSSLGVIG SAVAGILGYL INFLAYIIYL IYLNKRNLTY LTFKTIKLNK
     IDFNLLVVVS LIGMASFFRN GSLSIVTTFY ESFLVNLTKA TTDKNDVFYL TLLTGPIAIS
     NLASAAIFGL LQGVRTVSSY KFGQKKYDEI KKINIYTVII CISFGSLIYL LTAVAFGKQI
     LSSFFDVSDQ NLDLANYFSL IVQAQVFFVA TGANSQQYFQ NTNRVLYSWI VSLTHGLFVF
     IPLLFIFQAI TLQTNNIEVF IWLLTANAAL AGLINIAFGQ IHTNLFMDKY FANPPQNKLV
     KFIEKYS