ID   Y447_TREPA              Reviewed;         374 AA.
AC   O83461;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein TP_0447;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0447;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000520; AAC65436.1; -; Genomic_DNA.
DR   PIR; G71324; G71324.
DR   RefSeq; WP_010881895.1; NC_021490.2.
DR   AlphaFoldDB; O83461; -.
DR   STRING; 243276.TPANIC_0447; -.
DR   EnsemblBacteria; AAC65436; AAC65436; TP_0447.
DR   KEGG; tpa:TP_0447; -.
DR   eggNOG; COG3118; Bacteria.
DR   HOGENOM; CLU_063467_0_0_12; -.
DR   OMA; WIGEVYR; -.
DR   OrthoDB; 1691271at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..374
FT                   /note="Uncharacterized protein TP_0447"
FT                   /id="PRO_0000014248"
SQ   SEQUENCE   374 AA;  43127 MW;  F7EE331ED9743320 CRC64;
     MNNLIKAYAA GVMSAAFLFG SEGRVRSESD RVRGEDPWHL LQWAQVVYER EEFGDTLRYA
     QRARALRREQ VEHQCRVLLR ARTRAESAGI PETLSDLYAL LKSRGETDAC EVLDAIFLTH
     APHVFQNSVS KLLQWLKDSA AFPEAELLLG KVFEGEGEYA QALQHYRNAW DTRAQLVVPD
     ARFDIIYAMA NVSRLLSQQD EREKYLLLVL SEDPLYSARE VWGKTLHAML RTIRSSNTVE
     KFFKLYRHRN VLALRAYQEL TEMYVRTDNI ERALPVSVLA ADIAISALDS FLQKIELTYQ
     YKDLADLFLR TGSHPTILKW ANEHGVWQTL LHFADLLYKK GLHAQARDMY YNLAEKCPAF
     EYARRAAYKL SLTL