ID   Y4483_MYCA1             Reviewed;         286 AA.
AC   A0QL30;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Uncharacterized oxidoreductase MAV_4483;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MAV_4483;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK65683.1; -; Genomic_DNA.
DR   RefSeq; WP_011726085.1; NC_008595.1.
DR   AlphaFoldDB; A0QL30; -.
DR   SMR; A0QL30; -.
DR   EnsemblBacteria; ABK65683; ABK65683; MAV_4483.
DR   GeneID; 66692494; -.
DR   KEGG; mav:MAV_4483; -.
DR   HOGENOM; CLU_023205_0_1_11; -.
DR   OMA; WPPFLYD; -.
DR   OrthoDB; 1035565at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR018170; Aldo/ket_reductase_CS.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43827; PTHR43827; 1.
DR   Pfam; PF00248; Aldo_ket_red; 2.
DR   PIRSF; PIRSF000097; AKR; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; SSF51430; 1.
DR   PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..286
FT                   /note="Uncharacterized oxidoreductase MAV_4483"
FT                   /id="PRO_0000380731"
FT   ACT_SITE        61
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         119
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         199..251
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   286 AA;  31341 MW;  776275C960998B14 CRC64;
     MTVIDEIYSS SSAIPTVALN DEAKMPVLGL GVAKLSDEET ESSVLAALEA GCRLIDTAAS
     YGNEAAVGRA IAASGIPREE LFVTTKLGTS RQGFHSAQES CKESLDRLGL DYLDLYLIHW
     PAPKLGKYVE SFEGMIEARE RGHVRSIGVS NFTEDLLATV IEETDEVPAV NQVELHPRLN
     QAELRQVHAQ HDVTTQSYSP LGVGRLIEEP TVTTIAAEYG RTPAQVLVRW NLQLDNVVVS
     RSSKPERVAE NLDVFDFTLE PEHMEAIEGL HDGTRVLHDP MTFMGT