ID   Y449_BUCAI              Reviewed;         196 AA.
AC   P57524;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   15-NOV-2002, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=UPF0056 membrane protein BU449;
GN   OrderedLocusNames=BU449;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB13147.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000003; BAB13147.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_240261.2; NC_002528.1.
DR   RefSeq; WP_010896122.1; NC_002528.1.
DR   AlphaFoldDB; P57524; -.
DR   STRING; 107806.10039113; -.
DR   PRIDE; P57524; -.
DR   EnsemblBacteria; BAB13147; BAB13147; BAB13147.
DR   KEGG; buc:BU449; -.
DR   PATRIC; fig|107806.10.peg.459; -.
DR   eggNOG; COG2095; Bacteria.
DR   HOGENOM; CLU_079909_1_1_6; -.
DR   OMA; IRMIFPQ; -.
DR   BioCyc; BAPH107806:GBZJ-442-MON; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002771; Multi_antbiot-R_MarC.
DR   PANTHER; PTHR33508; PTHR33508; 1.
DR   Pfam; PF01914; MarC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..196
FT                   /note="UPF0056 membrane protein BU449"
FT                   /id="PRO_0000156910"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   196 AA;  22056 MW;  86D841D9073C93DD CRC64;
     MTEIISTTIL LVLIMDPLGN LPIFMTILKH LDVKRRRIVV IREMIIALIV MLLFLFVGEK
     ILIILNLKTE TVSISGGVIL FLIAIKMIFP SEDNNNEISS SEEPFLVPLA IPLVAGPSLL
     ATLMLLSHQY LHHMFYLVGS LLISWFFTVI ILLSSSLFLK LFGSKGVNAL ERLMGLVLIM
     LSTQMFLDGI RAWFKN