ID   Y4526_NOCFA             Reviewed;         995 AA.
AC   Q5YR14;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0182 protein NFA_45260 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=NFA_45260;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; AP006618; BAD59377.1; -; Genomic_DNA.
DR   RefSeq; WP_011211061.1; NC_006361.1.
DR   AlphaFoldDB; Q5YR14; -.
DR   SMR; Q5YR14; -.
DR   STRING; 247156.NFA_45260; -.
DR   EnsemblBacteria; BAD59377; BAD59377; NFA_45260.
DR   GeneID; 61135133; -.
DR   KEGG; nfa:NFA_45260; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..995
FT                   /note="UPF0182 protein NFA_45260"
FT                   /id="PRO_0000157726"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          904..957
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   995 AA;  109357 MW;  4DD5EA7DEED0E082 CRC64;
     MGMRPPSGLP SLSRRSRVLL VAAVVLAALL LLGPRFTDAY TNWLWFGEVG FREVFLTVVV
     TRIILFAAVA LFVGATVWLA LLLAYRTRPV FVPMAGPNDP IARYRTTVMS RLKTFGIGIP
     VLLGLLAGLV AQSNWVTVQL FLNGGDFGEQ DPQFHLDVGF YAFDLPFYRM VLNWMFVAVV
     IAFFASLVTH YIFGGLRLSG REGTLTRPAR IQLAVIAGLF VLLKAVAYWF DRYDLLSSSR
     KEPTFYGGSF TDINAVLPAK LILLAIAVIC AVAFFAGVVL RDLRVPAMAA ALLVLSSVLV
     GAVYPLVVEQ FSVRPNAADK ESEYIERNIA ATRQAFGITS DKIEYKDYKG ESDKNPLDVP
     VDAATIGNAR LLDPNILSPT FTQLRQLKNF YGFPESLDID RYNLDGNLQD YIVAARELSP
     AALTGNQTDW INKHTVYTHG NGFVAAPANR VNKPQSEDVA AGGSSDSGYP IFLVSDLFTP
     KDRQRIPVEQ PRIYFGELIS QSDPDYAIVG GAEGQAPREY DSDTAQYTYT GKGGVPIGNW
     FNRLAFAAKY AERNILFSSA IGDDSKIIFN RSPRERVQKV APWLTTDGNA YPAVVDERIV
     WIVDAYTTLD NYPYAQKTSL EGAVEDSIDK KTGRLLPRKE VSYIRNSVKA TVDAYDGTVT
     LYEVDSTDPV LKAWRGVFPG AVKPESEISP ELRAHFRYPE DLFKVQREML TKYHVDNPRE
     FFTNNAFWSV PSDPTIEGGS FNQPPYYVLL GDPKTNRPVF NLTSAMVGYN RQFLSAYISV
     RSDPDDYGKF TILRLPTDTQ TQGPQQTQNT MTTAPQVSQE KTLLSNSNKI RYGNLLTLPI
     ADGGILYVEP FYNERNTGPN TATFPQLLRV LVSYRDQAGS VKVGYASTLA EALNQVLPGA
     GSLATPFGGD PATRPQPGTA PPVVDSTQPP ADGGTPQPQT TPPPTGSAAK DAAAAELDRK
     IEAVRNAMRS GNFQDFGKAL EELEAAVKTY QDAGR