ID   Y452_LISIN              Reviewed;         248 AA.
AC   Q92EK7;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Uncharacterized oxidoreductase Lin0452;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=lin0452;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AL596165; CAC95684.1; -; Genomic_DNA.
DR   PIR; AD1489; AD1489.
DR   RefSeq; WP_003760438.1; NC_003212.1.
DR   AlphaFoldDB; Q92EK7; -.
DR   SMR; Q92EK7; -.
DR   STRING; 272626.lin0452; -.
DR   EnsemblBacteria; CAC95684; CAC95684; CAC95684.
DR   KEGG; lin:lin0452; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; EWEQMID; -.
DR   OrthoDB; 1261526at2; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..248
FT                   /note="Uncharacterized oxidoreductase Lin0452"
FT                   /id="PRO_0000054882"
FT   ACT_SITE        154
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         9..33
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         141
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   248 AA;  26808 MW;  EAE7EB01F110306F CRC64;
     MTIKNKVIII TGASSGIGEA TAILLAEKGA KLVLAARRVE KLEKIVQTIK ASSGEAIFAK
     TDVTKREDNK KLVELAIERY GKVDAIFLNA GIMPNSPLSA LKEDEWEQMI DINIKGVLNG
     IAAVLPSFIA QKSGHIIATS SVAGLKAYPG GAVYGATKWA VRDLMEVLRM ESAQEGTNIR
     TATIYPAAIN TELLETITDK ETEQGMTNLY KQYGVTPDRI ASIVAYAIDQ PEDINVNEFT
     VGPTTQPW