ID   Y453_METS3              Reviewed;         313 AA.
AC   A5UKD0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein Msm_0453 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=Msm_0453;
OS   Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=420247;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35061 / DSM 861 / OCM 144 / PS;
RX   PubMed=17563350; DOI=10.1073/pnas.0704189104;
RA   Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B.,
RA   Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.;
RT   "Genomic and metabolic adaptations of Methanobrevibacter smithii to the
RT   human gut.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007).
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DR   EMBL; CP000678; ABQ86658.1; -; Genomic_DNA.
DR   RefSeq; WP_011953896.1; NC_009515.1.
DR   AlphaFoldDB; A5UKD0; -.
DR   STRING; 420247.Msm_0453; -.
DR   EnsemblBacteria; ABQ86658; ABQ86658; Msm_0453.
DR   GeneID; 5217007; -.
DR   KEGG; msi:Msm_0453; -.
DR   PATRIC; fig|420247.28.peg.453; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   OMA; PGVVYFR; -.
DR   BioCyc; MSMI420247:GHWZ-459-MON; -.
DR   Proteomes; UP000001992; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..313
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   Msm_0453"
FT                   /id="PRO_1000129777"
FT   DOMAIN          131..189
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        142..161
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   313 AA;  35651 MW;  25549B09C006153C CRC64;
     MLNRSKMLQE IDNLLTSEGY KTSNIYDQGS FDLVARKNLL ILLLKTFLNI DSINEANAHE
     MKQLANIFLA SPIIIGEKSR NGILEEGVIY ERYDIPAISF ETLKNMILYK EYPEILADRG
     GYFVKVDGNV IKQYREEYSL SLKDLADLAH VSRATMYKYE NEIVRANTET AMILEEILNT
     KVTLDIDLLK PTISEDIEYS NVEGADDLSK LGYGILSTNK SPFDAVAKMK SSKDKSSLLT
     NVEKNRSEKT LKRMAIPLKD LSMITSSEPV FIINNDKIKD SLGTIPVIKS WELKEFENPS
     ELLKIIRERK DNM