ID   Y4557_MYCA1             Reviewed;         315 AA.
AC   A0QL99;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4557;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4557;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK66928.1; -; Genomic_DNA.
DR   RefSeq; WP_011726123.1; NC_008595.1.
DR   AlphaFoldDB; A0QL99; -.
DR   SMR; A0QL99; -.
DR   EnsemblBacteria; ABK66928; ABK66928; MAV_4557.
DR   GeneID; 66695643; -.
DR   KEGG; mav:MAV_4557; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; NDTWEIT; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..315
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4557"
FT                   /id="PRO_0000361111"
FT   BINDING         134
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         163..164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   315 AA;  34842 MW;  CB82697D3AFA6274 CRC64;
     MSTARTDDDS WEITESVGAT ALGVASARAA ETRSENPLIK DPFAQVFLDA AGDGVWNWHS
     APQLPPELIE AEPTIPLQQQ AMVSYMASRT AFFDSFFLEA TGAGIRQAVI LAAGLDARSW
     RLPWPAGTTV YELDQPRVLE FKESTLAEHG AQPACNRVAV PVDLRHDWPE ALRQAGFDAS
     APSVWSAEGL MPYLPAAAQD LLFDRIQGLT VAGSRVAVEA LGPKFLDPQA RAKRRERMDR
     IQALMARIDP DRAVPRTDEL WYFEEREDVG EWFGRHGWDV RVTPSDELMA GYGRPAPAEV
     RDFVPGNLFV AAQRR