ID   Y4558_MYCA1             Reviewed;         320 AA.
AC   A0QLA0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4558;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4558;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68771.1; -; Genomic_DNA.
DR   RefSeq; WP_011726124.1; NC_008595.1.
DR   AlphaFoldDB; A0QLA0; -.
DR   SMR; A0QLA0; -.
DR   EnsemblBacteria; ABK68771; ABK68771; MAV_4558.
DR   KEGG; mav:MAV_4558; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; WDITEGV; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..320
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4558"
FT                   /id="PRO_0000361112"
FT   REGION          291..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         132
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         161..162
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   320 AA;  35782 MW;  341D032965B834AF CRC64;
     MPRTDDDSWE ITESVGATAL GVAAARAAET ESENPLISDP FARVFLDAAG DGMWNWFAAP
     NLPAQIAEAE PDLKPRMQGM VDYMAARTAF FDNFFLAATR AGVRQVVILA AGLDSRAWRL
     PFEDGTTVYE LDQPRVLEFK ATTLAEYGAR PTCHLVSVPV DLRHDWPAAL RQAGFDAHAP
     SAWSAEGLLP FLPAAAQQLL FERVQTLAAP GSRIAVEAPG PDFLDEAARE RQRQTMQRVR
     DLMADLEPDR DIPDVQDLWY FEEREDVGDW LGRHGWDVTV TPAPELMARY DRRPPHDIED
     ATPQTRFVAA QRTERTRPDR