ID   Y4573_MYCA1             Reviewed;         313 AA.
AC   A0QLB4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4573;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4573;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68210.1; -; Genomic_DNA.
DR   RefSeq; WP_011726134.1; NC_008595.1.
DR   AlphaFoldDB; A0QLB4; -.
DR   SMR; A0QLB4; -.
DR   EnsemblBacteria; ABK68210; ABK68210; MAV_4573.
DR   KEGG; mav:MAV_4573; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PWGLAQM; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4573"
FT                   /id="PRO_0000361113"
FT   BINDING         129
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         158..159
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  33386 MW;  26BA10B9FF5E82DA CRC64;
     MTVPNDDTWG PATSVGTTAT MAAAARAIAT RDGVINDPFA EPLVRAVGVN FLTRWAIGEL
     VASDVDVEGS PWGLAQMPAA IAARTRYFDE FYADAAAAGI RQAVILASGL DTRAYRLDWP
     AGMTVFEIDQ PAVVEFKTTA LARLAAEPKA DLRTVAVDLR DDWSTALATA GLDSSKPTAW
     IAEGLFGYLA PEAQDRLLDA VTALSTPGSR LGSEAVPDTA DMDPHAARQR MRAATAKWRD
     HGFELDVDVI SFAGERHDVG AYLQALGWTT VATPMAELLA DQGLPAIARA DDDRQTMNGV
     TYYTSTLGTG RQR