ID   Y4584_MYCA9             Reviewed;         308 AA.
AC   B1ML08;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4584c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_4584c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM64653.1; -; Genomic_DNA.
DR   RefSeq; WP_005079766.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1ML08; -.
DR   SMR; B1ML08; -.
DR   EnsemblBacteria; CAM64653; CAM64653; MAB_4584c.
DR   GeneID; 66970014; -.
DR   KEGG; mab:MAB_4584c; -.
DR   OMA; DSMPPTL; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..308
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_4584c"
FT                   /id="PRO_0000361124"
FT   BINDING         131
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         160..161
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   308 AA;  33674 MW;  1CE308AC8247AC90 CRC64;
     MTNIEDKDWS RSEGDSWDIV SSVGFTALGV AAARAVENRE ADPLVRDPYA EHFVRAAGEP
     HLIGLLDSSE PKPPNPGTAP RHIGLRSKFF DEFFINATNS GCKQAVILAA GLDVRAHRLP
     WPAGTKVFEL DQPQVLEFKD RVLAEHDATP TSDRREIAVD LRDDWPAALL AAGFDPEVPT
     AWSAEGLIIY LPSAAQDLLF ERVVALSAPG SQVAVEATRG RPDIAKWGEM QKKYADEGHP
     MSKVDITTLF YDEERADVAE WLAARGWKVQ GSHALELAAA YGVEIPELPE DVVEVVKQGN
     YVTAVLPS