ID   Y4585_MYCA9             Reviewed;         308 AA.
AC   B1ML09;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4585c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_4585c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM64654.1; -; Genomic_DNA.
DR   RefSeq; WP_005079765.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1ML09; -.
DR   SMR; B1ML09; -.
DR   EnsemblBacteria; CAM64654; CAM64654; MAB_4585c.
DR   GeneID; 66970015; -.
DR   KEGG; mab:MAB_4585c; -.
DR   OMA; WDINESV; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..308
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_4585c"
FT                   /id="PRO_0000361125"
FT   BINDING         131
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         160..161
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   308 AA;  33886 MW;  8588A9FF2C1AE707 CRC64;
     MTSTDQGSWA RSEGDSWDIV SSVGYTALGV SAQRAVESER PDALIDDPFA KHFVLAAGEP
     HLIETITKRD APQASPFEYL RGMGMRSRFF DEFFLEAAAS GITQAVILAA GLDARAHRLA
     WPAGVTVYEL DQPQVLAFKD GVYAQQGAEP TCDRRTVAVD LRDDWPAALK EAGFDAGRPT
     AWSAEGLLPY LPAAAQELLF ERMVELSAPG SRAAIEGPTG TLGMSQFAKV EQKYRSEKDT
     FGKIDITELF YDEEKTPPVE WFSVRGWSTQ GLDMFDLAER YGVRHPEVPE DIRELAGAMH
     YLTCTLPA