ID   Y4586_MYCA9             Reviewed;         302 AA.
AC   B1ML10;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4586c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_4586c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM64655.1; -; Genomic_DNA.
DR   RefSeq; WP_005089589.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1ML10; -.
DR   SMR; B1ML10; -.
DR   EnsemblBacteria; CAM64655; CAM64655; MAB_4586c.
DR   GeneID; 66970016; -.
DR   KEGG; mab:MAB_4586c; -.
DR   OMA; WVGVRTR; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..302
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_4586c"
FT                   /id="PRO_0000361126"
FT   BINDING         122
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         151..152
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   302 AA;  32513 MW;  7154532DF3B10F65 CRC64;
     MVRTEGDSWD IVTSVGYTAL AVAAGRALDA KLDPPLAHDD HAAAFVAAAG APQLAAAVAT
     ADMTSSAAFN AQWVGVRTRF FDNFFADAAG AGVRQHVILA AGLDSRAYRL PWPAITTVFE
     LDQPKVLQFK DEVLKRSGAQ PSARRVTVAV DLRDDWPAAL REAGFDATQP TGWILEGLLP
     YLPGAAQDAL FERLNDMSAP GSRVAAELGP EPGELERLAA SIKTVVGETS DGETQPNLRD
     LWFDDPRLDT KTWLGERGWT VTEANLVDAA VAYGRPLRDL PPAFENFLST KFFTAVQDHP
     RG