Y4586_MYCA9
ID Y4586_MYCA9 Reviewed; 302 AA.
AC B1ML10;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4586c;
DE EC=2.1.1.-;
GN OrderedLocusNames=MAB_4586c;
OS Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS 13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacteroides; Mycobacteroides abscessus.
OX NCBI_TaxID=561007;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC 1543;
RX PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA Gaillard J.L.;
RT "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT Mycobacterium abscessus.";
RL PLoS ONE 4:E5660-E5660(2009).
CC -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC activity. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU458896; CAM64655.1; -; Genomic_DNA.
DR RefSeq; WP_005089589.1; NZ_MLCG01000001.1.
DR AlphaFoldDB; B1ML10; -.
DR SMR; B1ML10; -.
DR EnsemblBacteria; CAM64655; CAM64655; MAB_4586c.
DR GeneID; 66970016; -.
DR KEGG; mab:MAB_4586c; -.
DR OMA; WVGVRTR; -.
DR Proteomes; UP000007137; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR011610; CHP00027_methylltransferase.
DR InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF04072; LCM; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
DR TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE 3: Inferred from homology;
KW Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT CHAIN 1..302
FT /note="Putative S-adenosyl-L-methionine-dependent
FT methyltransferase MAB_4586c"
FT /id="PRO_0000361126"
FT BINDING 122
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 151..152
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
SQ SEQUENCE 302 AA; 32513 MW; 7154532DF3B10F65 CRC64;
MVRTEGDSWD IVTSVGYTAL AVAAGRALDA KLDPPLAHDD HAAAFVAAAG APQLAAAVAT
ADMTSSAAFN AQWVGVRTRF FDNFFADAAG AGVRQHVILA AGLDSRAYRL PWPAITTVFE
LDQPKVLQFK DEVLKRSGAQ PSARRVTVAV DLRDDWPAAL REAGFDATQP TGWILEGLLP
YLPGAAQDAL FERLNDMSAP GSRVAAELGP EPGELERLAA SIKTVVGETS DGETQPNLRD
LWFDDPRLDT KTWLGERGWT VTEANLVDAA VAYGRPLRDL PPAFENFLST KFFTAVQDHP
RG