ID   Y4587_MYCA9             Reviewed;         310 AA.
AC   B1ML11;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4587c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_4587c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM64656.1; -; Genomic_DNA.
DR   RefSeq; WP_005089590.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1ML11; -.
DR   SMR; B1ML11; -.
DR   EnsemblBacteria; CAM64656; CAM64656; MAB_4587c.
DR   GeneID; 66970017; -.
DR   KEGG; mab:MAB_4587c; -.
DR   OMA; DLWFDDE; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..310
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_4587c"
FT                   /id="PRO_0000361127"
FT   BINDING         126
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         155..156
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   310 AA;  33830 MW;  FCCBC748BFB3F994 CRC64;
     MARTEGDTWD IVTSVGATAL VVSAMRAIEA RKPEPLARDD YAQHFVAATK AEAPLFSELL
     EDPEAAQAPD IQLFSSYLGA RTKYFDEFFL TAGNAGVRQA VILAAGLDVR GYRLPWAAGT
     TVYELDLPKV LEFKKQVLDE HNARATATVL DLHVDLRDDW PTVLKAAGFD PAQPTAWLAE
     GLLPFLPGAA QDLLFERIAD LSAPGSRVAV EDFGAPGNQA DRMSNAMQNE EGALQRIFKS
     IVEEDAPPSS LWFGDEREDP ARWLTGHGWT VEATTAGELL KRYNRVPLAG EHELTDAMGQ
     SRYFTAVLGA