ID   Y4606_MYCA9             Reviewed;         316 AA.
AC   B1ML30;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4606c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAB_4606c;
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS   13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC   1543;
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CU458896; CAM64675.1; -; Genomic_DNA.
DR   RefSeq; WP_005079748.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1ML30; -.
DR   SMR; B1ML30; -.
DR   EnsemblBacteria; CAM64675; CAM64675; MAB_4606c.
DR   GeneID; 66970036; -.
DR   KEGG; mab:MAB_4606c; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..316
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAB_4606c"
FT                   /id="PRO_0000361128"
FT   BINDING         137
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         166..167
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   316 AA;  34920 MW;  5AC5CFFDA5F21448 CRC64;
     MTGTTTARSD DDSWDIASSV GATAVMVAAA RAAETRSASP LIQDPFAQLL VERAGSGAWS
     VLASDGLRQQ LAELDPDADR VMQYAVDYQA VRTRFFDGFF ERAAHAGITQ VVILAAGLDS
     RAYRLDWPAG TTVYEIDQPL VLQYKRHTLD AHDVRSACLR REVPVDLRQD WPAALQREGF
     DVAEPTAWLA EGLLMYLPTE AQDRLFELIV DQSAPGSRIA VEAVGPDNDK RQEFRSKMRA
     HFDRARKLAG MDGESLDVGS LMYHDENRTD VPQWLAGRGW TVRAIPAEVE MAEAGRPGYI
     EEDLRGNTLI EAELKG