ID   Y4654_MYCGI             Reviewed;        1004 AA.
AC   A4TFF8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=UPF0182 protein Mflv_4654 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=Mflv_4654;
OS   Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS   PYR-GCK)).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYR-GCK;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; CP000656; ABP47122.1; -; Genomic_DNA.
DR   RefSeq; WP_011895490.1; NC_009338.1.
DR   AlphaFoldDB; A4TFF8; -.
DR   SMR; A4TFF8; -.
DR   STRING; 350054.Mflv_4654; -.
DR   EnsemblBacteria; ABP47122; ABP47122; Mflv_4654.
DR   KEGG; mgi:Mflv_4654; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   OrthoDB; 170146at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1004
FT                   /note="UPF0182 protein Mflv_4654"
FT                   /id="PRO_1000088007"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          896..960
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        912..930
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1004 AA;  109567 MW;  76C295B44D83A29F CRC64;
     MGMRPAARMP SLTQRSRFLI AVSAVLVLLL LLGPRFIDTY VDWLWFGELG YRSVFTTQII
     TRLVIFFVVA ILVGAVVFAG LALAYRTRPV FVPTAGPNDP IARYRTAVMA RLRLIGIGVP
     LAIGVLAGFV GQSYWQRVQL FLHGGDFGVS DPQFGIDLGF YAFDLPFYRL VLTYLFVGVF
     LAFLANLLGH YLFGGIRLAG RSGALSRAAR IQLITLVGLL MLLKAVAYWF DRYELLSHTR
     GGKPFTGAGY TDINAVLPAK LILMAIAVIC AVAVFSAIFL RDLRIPAIGV VLLLLSSLVV
     GAGWPLVVEQ ISVRPNAAQK ESEYISRSIT ATRQAYGLTE ESVTYRDYPG NASATAQQVA
     ADRATTSNIR VLDPNIVAPA FTQFQQGKNF YFFPDQLNMD RYRDDSGNLR DYVVAARELN
     PDRLIDNQRD WINRHTVFTH GNGFIASPAN TVRGIANDPN QNGGYPEFLA SVVGANGEVS
     SPGPAPLAQP RIYFGPVIAS AADDYAIVGE SGTPREYDYE TNTDTRNYTY TGSGGVPIGN
     WLTRSVFAAK YAERNFLFSN VINENSKILF NRDPADRVEA VAPWLTTDTT VYPAIVNERI
     VWIVDGYTTL DNYPYSELST LSSVTTDSNE VAQNRLQLDK QVSYIRNSVK ATVDAYDGTV
     TLYAQDEQDP VLQAWMKVFP DSVKPKSDIT PELQEHLRYP EDLFKVQRAL LAKYHVDDPV
     TFFSTSDFWD VPLDPNPTAS SYQPPYYIVA KDLAENNGSA SFQLTSAMNR FRRDFLAAYI
     SASSDPETYG RLTVLTVPGQ VNGPKLAFNA ISTDTAISTE LGQIGRDGQN RIRWGNLLTL
     PMGDGGLLYV APIYASPGNT DAASTYPRLI RVAMMYNDQI GYGPTVRDAL TDLFGPGADA
     TATGPAATEP PAGQAPQTQG NNTAPPAAQP PNRQGQAPAG RPEVPVAVPP TGPTQLSAAK
     SAALQDVNAA LDALRGAQES GDFAQYGEAL QRLDDAVNKY QETD