ID   Y465_TREPA              Reviewed;         290 AA.
AC   O83478;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Uncharacterized protein TP_0465;
GN   OrderedLocusNames=TP_0465;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65457.1; -; Genomic_DNA.
DR   PIR; C71321; C71321.
DR   RefSeq; WP_010881914.1; NC_021490.2.
DR   AlphaFoldDB; O83478; -.
DR   IntAct; O83478; 10.
DR   STRING; 243276.TPANIC_0465; -.
DR   EnsemblBacteria; AAC65457; AAC65457; TP_0465.
DR   GeneID; 57878988; -.
DR   KEGG; tpa:TP_0465; -.
DR   HOGENOM; CLU_1045615_0_0_12; -.
DR   OMA; ENGRNDY; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..290
FT                   /note="Uncharacterized protein TP_0465"
FT                   /id="PRO_0000202258"
FT   TRANSMEM        5..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  32670 MW;  0C5771A7EA13FD08 CRC64;
     MSQVLTVLHA LSSPPWICLL SFNRMVLARQ CAFVLVSCVV PCVAGAVLSS CMPFYARTEG
     LTLKRVYFEK AGKTDATLAL HVTLEYPAPP EEYFYLEVEE LRTGMRWVFG EKDTRVYIAT
     DELHPGRRML RVGGMQYPWG DFPAGTYVVY VRDSTGTYAQ QRVTLGAGYP AHEPFPFSFS
     VDAQRWTLSA PAQPALVGPF TAHTHTSLVL LTRDYRTVAQ HPLSLTSLPN ARLSSPRVHT
     FEASMDALKT THQDAYYLQC VVEDFQRSWR FISQPHRLYP EDALSEQAPP