ID   Y4705_DICDI             Reviewed;         259 AA.
AC   Q555N6; Q86AU3;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 3.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Glutathione S-transferase domain-containing protein DDB_G0274705;
GN   ORFNames=DDB_G0274705;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the GST superfamily. {ECO:0000305}.
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DR   EMBL; AAFI02000012; EAL70245.2; -; Genomic_DNA.
DR   RefSeq; XP_644030.3; XM_638938.2.
DR   AlphaFoldDB; Q555N6; -.
DR   SMR; Q555N6; -.
DR   STRING; 44689.DDB0304359; -.
DR   PaxDb; Q555N6; -.
DR   GeneID; 8619460; -.
DR   KEGG; ddi:DDB_G0274705; -.
DR   dictyBase; DDB_G0274705; -.
DR   eggNOG; KOG0867; Eukaryota.
DR   HOGENOM; CLU_011226_14_4_1; -.
DR   InParanoid; Q555N6; -.
DR   OMA; ITQNTPN; -.
DR   PhylomeDB; Q555N6; -.
DR   PRO; PR:Q555N6; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..259
FT                   /note="Glutathione S-transferase domain-containing protein
FT                   DDB_G0274705"
FT                   /id="PRO_0000363846"
FT   DOMAIN          7..96
FT                   /note="GST N-terminal"
FT   DOMAIN          102..232
FT                   /note="GST C-terminal"
SQ   SEQUENCE   259 AA;  30073 MW;  E5559CF46CCEB1D9 CRC64;
     MIEINNKIDY IFYTNNTPNT YKIQLILLEL QKEYGITFES RFINVFKKEN YSDDYIKINP
     NKKVPAIVDQ TGEKPFIVFE SVSILIYLAQ KFNTFLPDFK TNPLENSEVI TWTVWQAANL
     GPAFGQYFHF SFFSPTVQEY SLHRFNNEAQ RILRLLDDRL SSTYIGGNEF SIADIASAGW
     LLYLNSAPLY NATKERFPNI FKWLDLINQR ESIKQVNQSI SDGFKNFNPS LLRALFTNDP
     ELINAKAPIG IENVILKYD