ID   Y473_TREPA              Reviewed;         214 AA.
AC   O83486;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Uncharacterized protein TP_0473;
GN   OrderedLocusNames=TP_0473;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65467.1; -; Genomic_DNA.
DR   PIR; G71318; G71318.
DR   RefSeq; WP_010881922.1; NC_021490.2.
DR   AlphaFoldDB; O83486; -.
DR   IntAct; O83486; 2.
DR   STRING; 243276.TPANIC_0473; -.
DR   EnsemblBacteria; AAC65467; AAC65467; TP_0473.
DR   KEGG; tpa:TP_0473; -.
DR   HOGENOM; CLU_1288413_0_0_12; -.
DR   OMA; FFLISWS; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..214
FT                   /note="Uncharacterized protein TP_0473"
FT                   /id="PRO_0000202261"
FT   TRANSMEM        4..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   214 AA;  24002 MW;  1497AA7E15DFAE92 CRC64;
     MVTVSIVEIF LIISLPLLFF SSFADAGDPL QELISFVHGA VLAVPLLLLR SFFLGYYPPD
     SALVEEQWMR FFLFDYVFPL FCLPFFLFTS RSLERVSLVS GVSALFGAYT SFFFVHVYTQ
     LNDPDLLARV MTLVLYMTNL LQLHAHVSFS MRTRLPLLGL IAALCIFLLM GAFSATVMTL
     CFFNARTVVY TSMLAGAGGV ALLTHFFAVR INVR