ID   Y474_TREPA              Reviewed;         245 AA.
AC   O83487;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Probable transcriptional regulatory protein TP_0474 {ECO:0000255|HAMAP-Rule:MF_00693};
GN   OrderedLocusNames=TP_0474;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00693}.
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DR   EMBL; AE000520; AAC65461.1; -; Genomic_DNA.
DR   PIR; H71318; H71318.
DR   RefSeq; WP_010881923.1; NC_021490.2.
DR   AlphaFoldDB; O83487; -.
DR   SMR; O83487; -.
DR   IntAct; O83487; 10.
DR   STRING; 243276.TPANIC_0474; -.
DR   EnsemblBacteria; AAC65461; AAC65461; TP_0474.
DR   GeneID; 57878995; -.
DR   KEGG; tpa:TP_0474; -.
DR   eggNOG; COG0217; Bacteria.
DR   HOGENOM; CLU_062974_2_2_12; -.
DR   OMA; ETIMYEG; -.
DR   OrthoDB; 1304328at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..245
FT                   /note="Probable transcriptional regulatory protein TP_0474"
FT                   /id="PRO_0000175922"
SQ   SEQUENCE   245 AA;  26326 MW;  EE57DDB2031B50D5 CRC64;
     MSGHSKWATI KHAKGAADAK RGQLFTKFIK EISVAARMAG GDPQANPRLR TAILKARAAN
     MPKDNIERAI KKGTGELSGS SYEELVYEGY APGGVAVLVE VLTDNKNRAA ANVRNLFSRN
     GGNLGSAGSV SYMFNRKGVI EYDSEQVDEE ALMELALEAG AEDIQNAGGV LTVTTVPGTF
     ETVLESLQAK GWESLSAGIS MVPDTYLALD EETARKVLKM IDRLEEEEDV QAVYSNADIP
     SELVL