ID   Y4756_STRAW             Reviewed;         112 AA.
AC   Q82E60;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UPF0060 membrane protein SAV_4756 {ECO:0000255|HAMAP-Rule:MF_00010};
GN   OrderedLocusNames=SAV_4756;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00010};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00010}.
CC   -!- SIMILARITY: Belongs to the UPF0060 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00010}.
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DR   EMBL; BA000030; BAC72468.1; -; Genomic_DNA.
DR   RefSeq; WP_010986179.1; NZ_JZJK01000077.1.
DR   AlphaFoldDB; Q82E60; -.
DR   STRING; 227882.SAV_4756; -.
DR   DNASU; 1215508; -.
DR   EnsemblBacteria; BAC72468; BAC72468; SAVERM_4756.
DR   KEGG; sma:SAVERM_4756; -.
DR   eggNOG; COG1742; Bacteria.
DR   HOGENOM; CLU_117653_0_1_11; -.
DR   OMA; WLWAVEG; -.
DR   OrthoDB; 1991345at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_00010; UPF0060; 1.
DR   InterPro; IPR003844; UPF0060.
DR   PANTHER; PTHR36116; PTHR36116; 1.
DR   Pfam; PF02694; UPF0060; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..112
FT                   /note="UPF0060 membrane protein SAV_4756"
FT                   /id="PRO_0000162352"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
SQ   SEQUENCE   112 AA;  11920 MW;  3AA0B616260DF4C3 CRC64;
     MLVLRSAALF VAAALFEIGG AWLVWQGVRE HRGWLWIGAG VMALGVYGFV ATLQPDAEFG
     RILAAYGGVF VAGSLAWGMV ADGYRPDRWD VTGALICLAG MTVIMYAPRG GN