Y4757_PSEAE
ID Y4757_PSEAE Reviewed; 216 AA.
AC P38102; Q9HV45;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2001, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Uncharacterized membrane protein PA4757;
GN OrderedLocusNames=PA4757;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=8169201; DOI=10.1128/jb.176.9.2532-2542.1994;
RA Kwon D.-H., Lu C.-D., Walthall D.A., Brown T.M., Houghton J.E.,
RA Abdelal A.T.;
RT "Structure and regulation of the carAB operon in Pseudomonas aeruginosa and
RT Pseudomonas stutzeri: no untranslated region exists.";
RL J. Bacteriol. 176:2532-2542(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR EMBL; U04992; AAA19047.1; -; Unassigned_DNA.
DR EMBL; U81259; AAB39251.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG08143.1; -; Genomic_DNA.
DR PIR; C55580; C55580.
DR PIR; F83051; F83051.
DR RefSeq; NP_253445.1; NC_002516.2.
DR RefSeq; WP_003095208.1; NZ_QZGE01000018.1.
DR AlphaFoldDB; P38102; -.
DR STRING; 287.DR97_2101; -.
DR PaxDb; P38102; -.
DR DNASU; 881750; -.
DR EnsemblBacteria; AAG08143; AAG08143; PA4757.
DR GeneID; 881750; -.
DR KEGG; pae:PA4757; -.
DR PATRIC; fig|208964.12.peg.4983; -.
DR PseudoCAP; PA4757; -.
DR HOGENOM; CLU_079569_3_1_6; -.
DR InParanoid; P38102; -.
DR OMA; AGVWCGD; -.
DR PhylomeDB; P38102; -.
DR BioCyc; PAER208964:G1FZ6-4869-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015190; F:L-leucine transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR GO; GO:0015820; P:leucine transport; IBA:GO_Central.
DR InterPro; IPR004778; Homoserine/Threonine_efflux.
DR InterPro; IPR001123; LeuE-type.
DR PANTHER; PTHR30086; PTHR30086; 1.
DR Pfam; PF01810; LysE; 1.
DR PIRSF; PIRSF006324; LeuE; 1.
DR TIGRFAMs; TIGR00949; 2A76; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..216
FT /note="Uncharacterized membrane protein PA4757"
FT /id="PRO_0000094747"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 109
FT /note="A -> G (in Ref. 1; AAA19047/AAB39251)"
FT /evidence="ECO:0000305"
FT CONFLICT 119
FT /note="P -> R (in Ref. 1; AAA19047/AAB39251)"
FT /evidence="ECO:0000305"
FT CONFLICT 122
FT /note="K -> Q (in Ref. 1; AAA19047/AAB39251)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 216 AA; 23249 MW; A30A08E714591B8D CRC64;
MPTLGITDFW TYVLGVVFVI LLPGPNSLFV LATSAQRGVA TGYRAACGVF LGDAVLMLLS
ALGVASLLKA EPMLFIGLKY LGAAYLFYLG VGMLRGAWRK LRNPEATAAQ AEQVDVHQPF
RKALLLSLSN PKAILFFISF FIQFVDPGYA YPGLSFLVLA VILELVSALY LSFLIFTGVR
LAAWFRRRQR LAAGATSGVG ALFVGFGVKL ATATLS
