ID   Y475_MYCLE              Reviewed;         251 AA.
AC   Q49645;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Probable transcriptional regulatory protein ML0475 {ECO:0000255|HAMAP-Rule:MF_00693};
GN   OrderedLocusNames=ML0475; ORFNames=B1177_C2_181, u1177b;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00693}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00011; AAA17094.1; -; Genomic_DNA.
DR   EMBL; AL583918; CAC29983.1; -; Genomic_DNA.
DR   PIR; S72730; S72730.
DR   RefSeq; NP_301420.1; NC_002677.1.
DR   RefSeq; WP_010907744.1; NC_002677.1.
DR   AlphaFoldDB; Q49645; -.
DR   SMR; Q49645; -.
DR   STRING; 272631.ML0475; -.
DR   EnsemblBacteria; CAC29983; CAC29983; CAC29983.
DR   KEGG; mle:ML0475; -.
DR   PATRIC; fig|272631.5.peg.836; -.
DR   Leproma; ML0475; -.
DR   eggNOG; COG0217; Bacteria.
DR   HOGENOM; CLU_062974_2_2_11; -.
DR   OMA; ETIMYEG; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..251
FT                   /note="Probable transcriptional regulatory protein ML0475"
FT                   /id="PRO_0000175847"
SQ   SEQUENCE   251 AA;  26614 MW;  8584C114E1F02E6C CRC64;
     MSGHSKWATT KHKKAVIDAR RGKMFARLIK NIEVAARVGG GDPVGNPTLY DAIQKAKKSS
     VPNGNIERAR KRGAGEEVGG ADWQVITYEG YAPNGVAVLI ECLTDNRNRA AGEVRVAMTR
     NGGAMADPGS VAYLFSRKGV VTLEKNGLTE DDVLAAVLDA GAEEVNDLGD SFEVIAEPGD
     LVAVRTALQD AGIDYESAEA SFQPSVSMPV DLDGARKVFK LVDALEDSDD VHNVWTNADV
     SDEVLAALDG E