Y4762_MYCUA
ID Y4762_MYCUA Reviewed; 310 AA.
AC A0PWG3;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_4762;
DE EC=2.1.1.-;
GN OrderedLocusNames=MUL_4762;
OS Mycobacterium ulcerans (strain Agy99).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=362242;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99;
RX PubMed=17210928; DOI=10.1101/gr.5942807;
RA Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.,
RA Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.;
RT "Reductive evolution and niche adaptation inferred from the genome of
RT Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL Genome Res. 17:192-200(2007).
CC -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC activity. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR EMBL; CP000325; ABL06682.1; -; Genomic_DNA.
DR AlphaFoldDB; A0PWG3; -.
DR SMR; A0PWG3; -.
DR STRING; 362242.MUL_4762; -.
DR EnsemblBacteria; ABL06682; ABL06682; MUL_4762.
DR KEGG; mul:MUL_4762; -.
DR eggNOG; COG3315; Bacteria.
DR HOGENOM; CLU_056160_2_1_11; -.
DR OMA; PMDITEL; -.
DR Proteomes; UP000000765; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR011610; CHP00027_methylltransferase.
DR InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF04072; LCM; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
DR TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE 3: Inferred from homology;
KW Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT CHAIN 1..310
FT /note="Putative S-adenosyl-L-methionine-dependent
FT methyltransferase MUL_4762"
FT /id="PRO_0000361251"
FT BINDING 132
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 161..162
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
SQ SEQUENCE 310 AA; 34535 MW; DBE6FB1E4C68B24F CRC64;
MRTHDDTWDI RTSVGATAVM VAAARAVETS KPEPLIRDPY ARMLVTNANA GVIWEAMLDQ
EMVAKVEAID AETAATVEHM RSYQAVRTNF FDTYFADAVA AGIRQVVILA SGLDSRAYRL
DWPAGTTVYE IDQPQVLAYK SATLAENGVT PAAERREVAI DLRQDWPSAL RAAGFDPSAR
TAWLAEGLLM YLPAEAQDRL FTQIGELSCA GSRIAAETAG NHADERREQM RERFRKVAQT
LGLEQTIDVH ELIYHDPDRA PLGQWLNEHG WRANAQNACD EMHRVGRWVE GVPMADDKQA
YSDFVTAERL