ID   Y4778_PSEAE             Reviewed;         132 AA.
AC   Q9HV30;
DT   03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator PA4778;
GN   OrderedLocusNames=PA4778;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- DOMAIN: It contains a N-terminal DNA binding region and a C-terminal
CC       metal binding region. {ECO:0000250}.
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DR   EMBL; AE004091; AAG08164.1; -; Genomic_DNA.
DR   PIR; H83048; H83048.
DR   RefSeq; NP_253466.1; NC_002516.2.
DR   RefSeq; WP_003095248.1; NZ_QZGE01000018.1.
DR   AlphaFoldDB; Q9HV30; -.
DR   SMR; Q9HV30; -.
DR   STRING; 287.DR97_2123; -.
DR   PaxDb; Q9HV30; -.
DR   PRIDE; Q9HV30; -.
DR   DNASU; 881842; -.
DR   EnsemblBacteria; AAG08164; AAG08164; PA4778.
DR   GeneID; 881842; -.
DR   KEGG; pae:PA4778; -.
DR   PATRIC; fig|208964.12.peg.5005; -.
DR   PseudoCAP; PA4778; -.
DR   HOGENOM; CLU_060077_2_0_6; -.
DR   InParanoid; Q9HV30; -.
DR   OMA; HTLAFIK; -.
DR   PhylomeDB; Q9HV30; -.
DR   BioCyc; PAER208964:G1FZ6-4891-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   CollecTF; EXPREG_00001590; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:PseudoCAP.
DR   CDD; cd01108; HTH_CueR; 1.
DR   InterPro; IPR011789; CueR.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   InterPro; IPR015358; Tscrpt_reg_MerR_DNA-bd.
DR   Pfam; PF00376; MerR; 1.
DR   Pfam; PF09278; MerR-DNA-bind; 1.
DR   PRINTS; PR00040; HTHMERR.
DR   SMART; SM00422; HTH_MERR; 1.
DR   SUPFAM; SSF46955; SSF46955; 1.
DR   TIGRFAMs; TIGR02044; CueR; 1.
DR   PROSITE; PS50937; HTH_MERR_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..132
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   PA4778"
FT                   /id="PRO_0000098172"
FT   DOMAIN          1..69
FT                   /note="HTH merR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
FT   DNA_BIND        4..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00254"
SQ   SEQUENCE   132 AA;  15015 MW;  058ECD37D200CBEA CRC64;
     MNIGEAAKKS GLTPKMIRYY ESIELLRPAG RSASGYRHYN ENDLHTLAFI RRSRDLGFSL
     DEVGKLLTLW QDRQRASADV KALAAQHVRE LNRKIEELST LRDTLQDLVE HCQGDHRPDC
     PILKDLASGC CH