ID   Y4788_DICDI             Reviewed;         375 AA.
AC   Q54SG3;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Uncharacterized transmembrane protein DDB_G0282483;
GN   ORFNames=DDB_G0282483;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AAFI02000047; EAL66101.1; -; Genomic_DNA.
DR   RefSeq; XP_640076.1; XM_634984.1.
DR   AlphaFoldDB; Q54SG3; -.
DR   SMR; Q54SG3; -.
DR   PaxDb; Q54SG3; -.
DR   EnsemblProtists; EAL66101; EAL66101; DDB_G0282483.
DR   GeneID; 8623605; -.
DR   KEGG; ddi:DDB_G0282483; -.
DR   dictyBase; DDB_G0282483; -.
DR   eggNOG; ENOG502RE1Q; Eukaryota.
DR   HOGENOM; CLU_738574_0_0_1; -.
DR   InParanoid; Q54SG3; -.
DR   OMA; AFEINDQ; -.
DR   PRO; PR:Q54SG3; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; IBA:GO_Central.
DR   InterPro; IPR013945; Pkr1.
DR   PANTHER; PTHR28251; PTHR28251; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..375
FT                   /note="Uncharacterized transmembrane protein DDB_G0282483"
FT                   /id="PRO_0000351230"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        327..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          119..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..144
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..189
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        190..213
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   375 AA;  40387 MW;  5E827F2F4F82A841 CRC64;
     MAGNKKQVKK NTKPIVVDID DKPLLDTSNL DTAVQTSAST KKDGKKVTAT TTTTTPTPTP
     TPTPTPTTTT TTEKKSKEIE IVPTPSNVPA SISASTSNVV IAPAVEAQIT DDFSVVPEKN
     KNKKKINSTA TDGTTTTTNI PKPTPVRAPI TKKGNTAPRS QFHLLALDED DITFDETHSH
     KEEPKQPQQQ HSTKKSSSKQ QATQNVSSSS SSKKSKSKET KKVEPTPTTT TQRTTTTKST
     PTPTPTPTPA ATKVVEQPKE KSSPAPVKKE KEIKQNKKES EGFLFSLMES LITPGVPSVV
     YKIIYVALIG VLLFSLVPLY YSGLDSIYSY GVIALVLGLG ISLTLFISEI PRLQASKEQK
     SKSGNKKSTT RKVKA