Y4791_ARATH
ID Y4791_ARATH Reviewed; 434 AA.
AC B3H6K1; F4JQ10; O49690;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 2.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Uncharacterized protein At4g17910;
DE Flags: Precursor;
GN OrderedLocusNames=At4g17910; ORFNames=T6K21.90;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-197, AND NUCLEOTIDE SEQUENCE
RP [LARGE SCALE MRNA] OF 243-434.
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX835579; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC Sequence=CAA17134.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 3 genes: At4g17905, At4g17910 and At4g17915.; Evidence={ECO:0000305};
CC Sequence=CAB78793.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 3 genes: At4g17905, At4g17910 and At4g17915.; Evidence={ECO:0000305};
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DR EMBL; AL021889; CAA17134.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161547; CAB78793.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83967.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66934.1; -; Genomic_DNA.
DR EMBL; BX835579; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BX839372; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T05077; T05077.
DR RefSeq; NP_001328798.1; NM_001341246.1.
DR RefSeq; NP_193525.5; NM_117901.6.
DR AlphaFoldDB; B3H6K1; -.
DR BioGRID; 12808; 1.
DR STRING; 3702.AT4G17910.1; -.
DR PaxDb; B3H6K1; -.
DR PRIDE; B3H6K1; -.
DR ProteomicsDB; 242856; -.
DR EnsemblPlants; AT4G17910.1; AT4G17910.1; AT4G17910.
DR EnsemblPlants; AT4G17910.2; AT4G17910.2; AT4G17910.
DR GeneID; 827515; -.
DR Gramene; AT4G17910.1; AT4G17910.1; AT4G17910.
DR Gramene; AT4G17910.2; AT4G17910.2; AT4G17910.
DR KEGG; ath:AT4G17910; -.
DR Araport; AT4G17910; -.
DR TAIR; locus:2141080; AT4G17910.
DR eggNOG; KOG0411; Eukaryota.
DR HOGENOM; CLU_020802_2_2_1; -.
DR PRO; PR:B3H6K1; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; B3H6K1; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0032216; F:glucosaminyl-phosphatidylinositol O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IBA:GO_Central.
DR GO; GO:0072659; P:protein localization to plasma membrane; IBA:GO_Central.
DR InterPro; IPR009447; PIGW/GWT1.
DR PANTHER; PTHR20661; PTHR20661; 1.
DR Pfam; PF06423; GWT1; 1.
DR PIRSF; PIRSF017321; GWT1; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..434
FT /note="Uncharacterized protein At4g17910"
FT /id="PRO_0000355971"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 119
FT /note="I -> M (in Ref. 3; BX839372)"
FT /evidence="ECO:0000305"
FT CONFLICT 159
FT /note="A -> S (in Ref. 3; BX839372)"
FT /evidence="ECO:0000305"
FT CONFLICT 173
FT /note="W -> F (in Ref. 3; BX839372)"
FT /evidence="ECO:0000305"
FT CONFLICT 176..178
FT /note="GIK -> FII (in Ref. 3; BX839372)"
FT /evidence="ECO:0000305"
FT CONFLICT 187
FT /note="G -> F (in Ref. 3; BX839372)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 434 AA; 48520 MW; 4F22ACC51EDC53E1 CRC64;
MTFLLFQLLV LLRYSIGFHC KIDNNGVKSV TSKKNDDEKI VISRNWKAAI SLDFIFIVFP
MLLFFTVLSE WVYHGTGLLS LLVLILSVTA KRSFSGLQRG QSLSFRASVS SYRVALMLIT
CLCILAVDFT IFPRRYAKTE TYGTSLMDLG VGSFVLANAV VSRQARDVSS GNWITGIKAT
APLLLLGFIR LVTTSGVDYQ VHVTEYGVHW NFFFTLAAIS ILTSFVNIPA KYCGLLGFAV
LAGYQTWLLS GLNTYLLSDE RGTDIISKNK EGVYSILGYW GMYLLGVHLG YRLFYGKHTN
IRSTTSSIAR VFLVSLLLWI VTILFDNYVE RISRRTCNMP YVTWVLAQDL QALGIFMLSS
YIPLNKLSSL EEAIDQNLLA TFLLANLVTG MVNLTVDTIF ASPFSSLLIL TAYAFALSAI
IGTIHFSGFR LKFW