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Y4791_ARATH
ID   Y4791_ARATH             Reviewed;         434 AA.
AC   B3H6K1; F4JQ10; O49690;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Uncharacterized protein At4g17910;
DE   Flags: Precursor;
GN   OrderedLocusNames=At4g17910; ORFNames=T6K21.90;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-197, AND NUCLEOTIDE SEQUENCE
RP   [LARGE SCALE MRNA] OF 243-434.
RC   STRAIN=cv. Columbia;
RX   PubMed=14993207; DOI=10.1101/gr.1515604;
RA   Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA   Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA   Weissenbach J., Salanoubat M.;
RT   "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT   combined approach to evaluate and improve Arabidopsis genome annotation.";
RL   Genome Res. 14:406-413(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BX835579; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC       Sequence=CAA17134.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 3 genes: At4g17905, At4g17910 and At4g17915.; Evidence={ECO:0000305};
CC       Sequence=CAB78793.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 3 genes: At4g17905, At4g17910 and At4g17915.; Evidence={ECO:0000305};
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DR   EMBL; AL021889; CAA17134.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL161547; CAB78793.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002687; AEE83967.1; -; Genomic_DNA.
DR   EMBL; CP002687; ANM66934.1; -; Genomic_DNA.
DR   EMBL; BX835579; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BX839372; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; T05077; T05077.
DR   RefSeq; NP_001328798.1; NM_001341246.1.
DR   RefSeq; NP_193525.5; NM_117901.6.
DR   AlphaFoldDB; B3H6K1; -.
DR   BioGRID; 12808; 1.
DR   STRING; 3702.AT4G17910.1; -.
DR   PaxDb; B3H6K1; -.
DR   PRIDE; B3H6K1; -.
DR   ProteomicsDB; 242856; -.
DR   EnsemblPlants; AT4G17910.1; AT4G17910.1; AT4G17910.
DR   EnsemblPlants; AT4G17910.2; AT4G17910.2; AT4G17910.
DR   GeneID; 827515; -.
DR   Gramene; AT4G17910.1; AT4G17910.1; AT4G17910.
DR   Gramene; AT4G17910.2; AT4G17910.2; AT4G17910.
DR   KEGG; ath:AT4G17910; -.
DR   Araport; AT4G17910; -.
DR   TAIR; locus:2141080; AT4G17910.
DR   eggNOG; KOG0411; Eukaryota.
DR   HOGENOM; CLU_020802_2_2_1; -.
DR   PRO; PR:B3H6K1; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; B3H6K1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032216; F:glucosaminyl-phosphatidylinositol O-acyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IBA:GO_Central.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IBA:GO_Central.
DR   InterPro; IPR009447; PIGW/GWT1.
DR   PANTHER; PTHR20661; PTHR20661; 1.
DR   Pfam; PF06423; GWT1; 1.
DR   PIRSF; PIRSF017321; GWT1; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..434
FT                   /note="Uncharacterized protein At4g17910"
FT                   /id="PRO_0000355971"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        119
FT                   /note="I -> M (in Ref. 3; BX839372)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        159
FT                   /note="A -> S (in Ref. 3; BX839372)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        173
FT                   /note="W -> F (in Ref. 3; BX839372)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        176..178
FT                   /note="GIK -> FII (in Ref. 3; BX839372)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        187
FT                   /note="G -> F (in Ref. 3; BX839372)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   434 AA;  48520 MW;  4F22ACC51EDC53E1 CRC64;
     MTFLLFQLLV LLRYSIGFHC KIDNNGVKSV TSKKNDDEKI VISRNWKAAI SLDFIFIVFP
     MLLFFTVLSE WVYHGTGLLS LLVLILSVTA KRSFSGLQRG QSLSFRASVS SYRVALMLIT
     CLCILAVDFT IFPRRYAKTE TYGTSLMDLG VGSFVLANAV VSRQARDVSS GNWITGIKAT
     APLLLLGFIR LVTTSGVDYQ VHVTEYGVHW NFFFTLAAIS ILTSFVNIPA KYCGLLGFAV
     LAGYQTWLLS GLNTYLLSDE RGTDIISKNK EGVYSILGYW GMYLLGVHLG YRLFYGKHTN
     IRSTTSSIAR VFLVSLLLWI VTILFDNYVE RISRRTCNMP YVTWVLAQDL QALGIFMLSS
     YIPLNKLSSL EEAIDQNLLA TFLLANLVTG MVNLTVDTIF ASPFSSLLIL TAYAFALSAI
     IGTIHFSGFR LKFW
 
 
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