ID   Y479_MYCPA              Reviewed;         309 AA.
AC   Q743W2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Uncharacterized tRNA/rRNA methyltransferase MAP_0479;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_0479;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC       superfamily. RNA methyltransferase TrmH family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS02796.1; -; Genomic_DNA.
DR   RefSeq; WP_003877110.1; NC_002944.2.
DR   AlphaFoldDB; Q743W2; -.
DR   SMR; Q743W2; -.
DR   STRING; 262316.MAP_0479; -.
DR   EnsemblBacteria; AAS02796; AAS02796; MAP_0479.
DR   KEGG; mpa:MAP_0479; -.
DR   PATRIC; fig|262316.17.peg.510; -.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_021322_0_0_11; -.
DR   OMA; QVPPYEY; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR46429; PTHR46429; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   TIGRFAMs; TIGR00186; rRNA_methyl_3; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..309
FT                   /note="Uncharacterized tRNA/rRNA methyltransferase
FT                   MAP_0479"
FT                   /id="PRO_0000379576"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         261
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         281
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         290
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   309 AA;  32331 MW;  E3F426693EF9A109 CRC64;
     MAGNSRRRGA VRKAGTKKGP TVGSGGQRRR GLEGRGPTPP AHLRPNHPAA KRAQSPPRRP
     AKRTEETETV LGRNPVLECL RAGVPATALY VALGTEADER LTESVSRAAD SGISILEVPR
     ADLDRMTGNH LHQGIALQVP PYIYAHPDDL LEAAAGSLPA LLVALDNISD PRNLGAIVRS
     VAAFGGHGVL IPQRRSASVT AVAWRTSAGA AARIPVARAT NLTRTLQDWA DRGLRVIGLD
     AGGDTMLDDL DGSDPLVVVV GSEGKGLSRL VRQNCDEVVS IPMAGSAESL NASVAAGVVL
     AEISRQRRG