ID   Y482_STRPN              Reviewed;         182 AA.
AC   Q97SA4;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=UPF0397 protein SP_0482 {ECO:0000255|HAMAP-Rule:MF_01572};
GN   OrderedLocusNames=SP_0482;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- INTERACTION:
CC       Q97SA4; Q97RW5: miaA; NbExp=3; IntAct=EBI-6474861, EBI-6474857;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01572};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01572}.
CC   -!- SIMILARITY: Belongs to the UPF0397 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01572}.
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DR   EMBL; AE005672; AAK74641.1; -; Genomic_DNA.
DR   PIR; H95055; H95055.
DR   RefSeq; WP_000403169.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; Q97SA4; -.
DR   IntAct; Q97SA4; 1.
DR   STRING; 170187.SP_0482; -.
DR   EnsemblBacteria; AAK74641; AAK74641; SP_0482.
DR   GeneID; 60233838; -.
DR   KEGG; spn:SP_0482; -.
DR   eggNOG; COG4720; Bacteria.
DR   OMA; WWSWVIA; -.
DR   PhylomeDB; Q97SA4; -.
DR   BioCyc; SPNE170187:G1FZB-499-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01572; UPF0397; 1.
DR   InterPro; IPR009825; ECF_substrate-spec-like.
DR   InterPro; IPR022914; UPF0397.
DR   Pfam; PF07155; ECF-ribofla_trS; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..182
FT                   /note="UPF0397 protein SP_0482"
FT                   /id="PRO_0000260814"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
SQ   SEQUENCE   182 AA;  19343 MW;  CB48F8EC9534C794 CRC64;
     MEIKFTIKQV VAVGIGAALF VVIGMINIPT PVPNTSIQLQ YAVQALLSII FGPIIGLLVG
     LIGHAIKDSL VGYGLWWTWI IASGLFGLVV GLFRKYVRVI NGVFDWKDIL IFNLIQLLAN
     ALVWGVLAPL GDVVIYQEAA EKVFAQGIVA GIANGVSVAI AGTLLLLAYA GTQTRAGSLK
     KD