ID   Y484_TREPA              Reviewed;         671 AA.
AC   O83497;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized protein TP_0484;
GN   OrderedLocusNames=TP_0484;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65473.1; -; Genomic_DNA.
DR   PIR; B71320; B71320.
DR   RefSeq; WP_010881933.1; NC_021490.2.
DR   AlphaFoldDB; O83497; -.
DR   IntAct; O83497; 5.
DR   STRING; 243276.TPANIC_0484; -.
DR   EnsemblBacteria; AAC65473; AAC65473; TP_0484.
DR   KEGG; tpa:TP_0484; -.
DR   eggNOG; COG4254; Bacteria.
DR   HOGENOM; CLU_409343_0_0_12; -.
DR   OMA; MPANDAV; -.
DR   OrthoDB; 610676at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR006860; FecR.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF04773; FecR; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..671
FT                   /note="Uncharacterized protein TP_0484"
FT                   /id="PRO_0000202265"
FT   TRANSMEM        39..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   671 AA;  75838 MW;  FE746C96BF27B661 CRC64;
     MTDRRRSMSC VHFFPLKSRG FLPTLTSKKR SVKLSKQDAT VTVVILLLIL LLGWGYSRAL
     RLSQGKGNPI GRVFFYKKTA TRKKNNQALW LKLKDGVPVY HRDVLRTTTG SEAVIVFTDN
     SRLDIAENTM VRISHTGMKK KDVRLVTGAI RYARAAGNPA AHTVHVGKTT ISLSGDGQVN
     VRGGERDSTV EIARGEALLH DAQGQTLPLQ TFTQLATSRE DGTVRILHPT FVPLLPDQDA
     LLLTAEHTRS VGFVWLGDAT TVQPSVRLQI SRYADFSVIE TERKLTLPHE ANASRTTFKT
     SERLGEGRWF WRLVPQNGTA SAPRSFSVRR ARKVMLHTPR AQAVLSYRDA IPPTLFSWTS
     VEDVEQYRLL LSSRADFSAD VKTFSLRTPE ISVPGLGEGT YFWKVVPRFD EGIEDPVFAS
     EVGTFSIKQG KELHAPVALF PAEDEVLEHA DRENRMVIFT CEPIPEARRY VWTVKNMDAN
     ASPLVTTTSV PFLTVPMRSL RARLQEGTYQ WQVAWETRRS DRSPYSALRA FTVIEGMHAW
     EEEPETRDLI ALRAPSFVLR DMPALITEKY LLQHRALRCK WTAVHNAQRY TVTLKNKKTD
     AVLQTATTTG VEFSFTNLAH LEEGSFHWVI QAHTEQEGYE PASAQVVRAF TIRVSELERP
     RAKEIVHYEY H