ID   Y485_METJA              Reviewed;         337 AA.
AC   Q57909;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Probable sulfurtransferase {ECO:0000305};
DE            EC=2.8.1.- {ECO:0000305};
GN   OrderedLocusNames=MJ0485;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000250|UniProtKB:O58038};
CC       Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by
CC       three Cys residues. {ECO:0000250|UniProtKB:O58038};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000250|UniProtKB:O58038};
CC   -!- SIMILARITY: Belongs to the TtcA family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98476.1; -; Genomic_DNA.
DR   PIR; E64360; E64360.
DR   RefSeq; WP_010869986.1; NC_000909.1.
DR   AlphaFoldDB; Q57909; -.
DR   SMR; Q57909; -.
DR   STRING; 243232.MJ_0485; -.
DR   EnsemblBacteria; AAB98476; AAB98476; MJ_0485.
DR   GeneID; 1451347; -.
DR   KEGG; mja:MJ_0485; -.
DR   eggNOG; arCOG00042; Archaea.
DR   HOGENOM; CLU_830567_0_0_2; -.
DR   InParanoid; Q57909; -.
DR   OMA; DECPYSR; -.
DR   OrthoDB; 30824at2157; -.
DR   PhylomeDB; Q57909; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR011063; TilS/TtcA_N.
DR   InterPro; IPR035107; tRNA_thiolation_TtcA_Ctu1.
DR   Pfam; PF01171; ATP_bind_3; 1.
DR   PIRSF; PIRSF004976; ATPase_YdaO; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; ATP-binding; Iron; Iron-sulfur; Metal-binding; Nucleotide-binding;
KW   Reference proteome; Transferase.
FT   CHAIN           1..337
FT                   /note="Probable sulfurtransferase"
FT                   /id="PRO_0000106892"
FT   BINDING         83
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
FT   BINDING         172
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
FT   BINDING         175
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
FT   BINDING         179
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
FT   BINDING         206
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
FT   BINDING         284
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000250|UniProtKB:O58038"
SQ   SEQUENCE   337 AA;  39323 MW;  6FB9C66BB619F065 CRC64;
     MVEINLRELK KYANPFFLTI RKDKILVNNK RMARLSRTKM DKIEEEFGIP VIYSKTYEYV
     STKVGRFINK HKIIAPRDIV IVGLSGGKDS LLLLHLLEVY RRKYGIKLIA VTVDVNIGGI
     RPWKEDTEGV KLIKHHCEML NVPHIILKND LDVVELSEIL TKHSKGMEFS PCFSCSVIKR
     HLLGKLAKEI AENENIPYEK VKLAYGHNLD DNSDTILANI FKGERLKFMR PLTRFKYNEV
     DYQSFKIPLE ECIIIRPMLP ILERDIIKAL EECGIEYYKD KDMCPYSRDR GDSVRRRCHE
     ILEKLEEEIP NIREMVVSSA LKTVEYYSKN PYGEDNL