ID   Y4873_MYCA1             Reviewed;         301 AA.
AC   A0QM57;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4873;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4873;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK67737.1; -; Genomic_DNA.
DR   RefSeq; WP_011726304.1; NC_008595.1.
DR   AlphaFoldDB; A0QM57; -.
DR   SMR; A0QM57; -.
DR   EnsemblBacteria; ABK67737; ABK67737; MAV_4873.
DR   KEGG; mav:MAV_4873; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; NEQCAPA; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..301
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4873"
FT                   /id="PRO_0000361115"
FT   BINDING         126
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         155..156
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   301 AA;  32862 MW;  BCEA28E20EA384E5 CRC64;
     MRSEGDTWDI TTSVGSTALF VATARALEAQ KPDPLAVDPY AEIFCRAVGG SAADVLDGKD
     PDHQLKTDDF GVHFVNFQGA RTKYFDEYFR RAADAGVRQV VILAAGLDSR AYRLDWPAAT
     TIFELDQPQV LDFKREVLAG VDAHPRAERR EIAVDLREDW PQALRDSGFD PDKPSAWIAE
     GLLIYLPASA QEQLFTGIDA LAGHGSHVAV EEGAPMTPED FEAAVAAERA ANEQGEQRMF
     FQLVYNEQCA PAAEWFGSRG WTAVPTPLAD YLRQVGRPVP GPDTEAGPMI ARNTLVSAVR
     A