Y488_MYCTO
ID Y488_MYCTO Reviewed; 201 AA.
AC P9WK32; L0T6U2; P64711; Q11154;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Putative amino-acid transporter MT0507;
GN OrderedLocusNames=MT0507;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
CC {ECO:0000305}.
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DR EMBL; AE000516; AAK44730.1; -; Genomic_DNA.
DR PIR; C70744; C70744.
DR RefSeq; WP_003402377.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WK32; -.
DR EnsemblBacteria; AAK44730; AAK44730; MT0507.
DR KEGG; mtc:MT0507; -.
DR PATRIC; fig|83331.31.peg.536; -.
DR HOGENOM; CLU_087840_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR001123; LeuE-type.
DR InterPro; IPR004777; Lys/arg_exporter.
DR PANTHER; PTHR30086; PTHR30086; 1.
DR Pfam; PF01810; LysE; 1.
DR TIGRFAMs; TIGR00948; 2a75; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..201
FT /note="Putative amino-acid transporter MT0507"
FT /id="PRO_0000427724"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 201 AA; 20951 MW; E198975DF088E6E4 CRC64;
MMTLKVAIGP QNAFVLRQGI RREYVLVIVA LCGIADGALI AAGVGGFAAL IHAHPNMTLV
ARFGGAAFLI GYALLAARNA WRPSGLVPSE SGPAALIGVV QMCLVVTFLN PHVYLDTVVL
IGALANEESD LRWFFGAGAW AASVVWFAVL GFSAGRLQPF FATPAAWRIL DALVAVTMIG
VAVVVLVTSP SVPTANVALI I