Y4919_ARATH
ID Y4919_ARATH Reviewed; 595 AA.
AC Q8VZ67; O49677; Q56W66; Q56WA5; Q67ZS6;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Uncharacterized zinc finger CCHC domain-containing protein At4g19190;
GN OrderedLocusNames=At4g19190; ORFNames=T18B16.160;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16708.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g19190 and At4g19191.; Evidence={ECO:0000305};
CC Sequence=CAB78921.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At4g19190 and At4g19191.; Evidence={ECO:0000305};
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DR EMBL; AL021687; CAA16708.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161550; CAB78921.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84157.1; -; Genomic_DNA.
DR EMBL; AY065216; AAL38692.1; -; mRNA.
DR EMBL; AY133757; AAM91691.1; -; mRNA.
DR EMBL; AK176041; BAD43804.1; -; mRNA.
DR EMBL; AK222139; BAD95177.1; -; mRNA.
DR EMBL; AK222181; BAD95313.1; -; mRNA.
DR EMBL; AK229939; BAF01765.1; -; mRNA.
DR RefSeq; NP_193654.2; NM_118039.5.
DR AlphaFoldDB; Q8VZ67; -.
DR SMR; Q8VZ67; -.
DR STRING; 3702.AT4G19190.1; -.
DR iPTMnet; Q8VZ67; -.
DR PaxDb; Q8VZ67; -.
DR PRIDE; Q8VZ67; -.
DR ProteomicsDB; 242905; -.
DR EnsemblPlants; AT4G19190.1; AT4G19190.1; AT4G19190.
DR GeneID; 827658; -.
DR Gramene; AT4G19190.1; AT4G19190.1; AT4G19190.
DR KEGG; ath:AT4G19190; -.
DR Araport; AT4G19190; -.
DR TAIR; locus:2134741; AT4G19190.
DR eggNOG; KOG3794; Eukaryota.
DR HOGENOM; CLU_033287_0_0_1; -.
DR OMA; NSHREKH; -.
DR OrthoDB; 628972at2759; -.
DR PhylomeDB; Q8VZ67; -.
DR PRO; PR:Q8VZ67; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8VZ67; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IBA:GO_Central.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR040014; CIR1.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR041670; Znf-CCHC_6.
DR PANTHER; PTHR13151; PTHR13151; 1.
DR Pfam; PF10197; Cir_N; 1.
DR Pfam; PF15288; zf-CCHC_6; 1.
DR SMART; SM01083; Cir_N; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..595
FT /note="Uncharacterized zinc finger CCHC domain-containing
FT protein At4g19190"
FT /id="PRO_0000363411"
FT ZN_FING 211..228
FT /note="CCHC-type; degenerate"
FT REGION 112..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 110
FT /note="M -> T (in Ref. 4; BAF01765/BAD43804)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 595 AA; 69147 MW; 77F1E5ADE851EF5B CRC64;
MDGEGEGSGI RLSKRFAGGK VTGGSLEVDY KTKSGTAWSH SFLNQKPWHP LSYPNQRRKW
IAEQTHAQHD RRAEEVAREF AQEQEFFKQA ALISKKEREK IETMKAVSFM YVRPPGYDPE
SAKAAEYKDE KHKGQGSSTQ DPVADDNVGS RPEESQGGGE RTQERKKPRP KDVFGRALPT
EEEFEVLKNA PRMETGIPGR VKPFAVEVRN VKCLRCGNFG HQSGDRDCPL KDAVMPNEEL
RLKRDDPLTA IIAHTDPSEP LKWELKQKPG LSPPRGGFDP DDPNQQIVAE DIFDEYGGFL
EGSIPIEILK SMSSDKKRKS KKNKRHKKHS SRTVEETDES STGSEDSREK RGSKKRKKLK
KKSKKQYDSD SLSFEGSGSD SYRLSRRRHT KHVDPSASLK SEVYHQGNSH REKHYYDEKH
QKRKEIVDRP SASSDDSDYY RSNSSRKKRS EDDYKSHHRE RKQVHSNDPV SEKSQKQHYS
ESGKIQRVEK EHRYDERRHR YVDMESENRN RSEKKPRYDD RDSEKHHRSV KGKEKHVYEA
SDDPEEFSDR YRSTKKTESD SESNRRSRKK KHELSSEEEE GESRKHRYST NRRRN
