ID   Y493_RICPR              Reviewed;         231 AA.
AC   Q9ZD54;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Putative aldolase class 2 protein RP493;
GN   OrderedLocusNames=RP493;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000305};
CC   -!- SIMILARITY: Belongs to the aldolase class II family. {ECO:0000305}.
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DR   EMBL; AJ235272; CAA14945.1; -; Genomic_DNA.
DR   PIR; G71652; G71652.
DR   RefSeq; NP_220869.1; NC_000963.1.
DR   RefSeq; WP_004599090.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZD54; -.
DR   SMR; Q9ZD54; -.
DR   STRING; 272947.RP493; -.
DR   EnsemblBacteria; CAA14945; CAA14945; CAA14945.
DR   GeneID; 57569617; -.
DR   KEGG; rpr:RP493; -.
DR   PATRIC; fig|272947.5.peg.502; -.
DR   eggNOG; COG0235; Bacteria.
DR   HOGENOM; CLU_006033_0_2_5; -.
DR   OMA; REAHDWT; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.225.10; -; 1.
DR   InterPro; IPR001303; Aldolase_II/adducin_N.
DR   InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR   Pfam; PF00596; Aldolase_II; 1.
DR   SMART; SM01007; Aldolase_II; 1.
DR   SUPFAM; SSF53639; SSF53639; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..231
FT                   /note="Putative aldolase class 2 protein RP493"
FT                   /id="PRO_0000162936"
FT   BINDING         94
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         96
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         158
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  26850 MW;  F48D03ADCB36D0D8 CRC64;
     MDIKYNLAAA YKIMAYLSLD DHTYTHLSAR SKNADFYYIY PFGLRFEEVT TENLLKVSLD
     GKILEGEEYQ YNKTGYFIHG NIYKARPDVL AIFHYHTPAS TAVSALKCGL LPISQWALHF
     YDRISYHDYN SLVLDADKQS TKFVNDLKQN YVMLLRNHGA ITCGKTIHEA MFYTYHLEQA
     CKTQCLLNST IQQELIIPSV EICKKTVKDL LSFEEDLGKR DWEAWLRLIN M