ID   Y494_MYCTO              Reviewed;         242 AA.
AC   P9WMG6; L0T5J2; P67739; Q11159;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator MT0514;
GN   OrderedLocusNames=MT0514;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
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DR   EMBL; AE000516; AAK44737.1; -; Genomic_DNA.
DR   PIR; A70745; A70745.
DR   RefSeq; WP_003402414.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMG6; -.
DR   SMR; P9WMG6; -.
DR   EnsemblBacteria; AAK44737; AAK44737; MT0514.
DR   KEGG; mtc:MT0514; -.
DR   PATRIC; fig|83331.31.peg.544; -.
DR   HOGENOM; CLU_017584_9_5_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48008; SSF48008; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..242
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   MT0514"
FT                   /id="PRO_0000427307"
FT   DOMAIN          17..85
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        45..64
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   242 AA;  26015 MW;  3E927CFC4A6FC1C5 CRC64;
     MVEPMNQSSV FQPPDRQRVD ERIATTIADA ILDGVFPPGS TLPPERDLAE RLGVNRTSLR
     QGLARLQQMG LIEVRHGSGS VVRDPEGLTH PAVVEALVRK LGPDFLVELL EIRAALGPLI
     GRLAAARSTP EDAEALCAAL EVVQQADTAA ARQAADLAYF RVLIHSTRNR ALGLLYRWVE
     HAFGGREHAL TGAYDDADPV LTDLRAINGA VLAGDPAAAA ATVEAYLNAS ALRMVKSYRD
     RA