Y4967_ARATH
ID Y4967_ARATH Reviewed; 362 AA.
AC Q9SZ83; Q56ZU4; Q94AR5;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=Uncharacterized oxidoreductase At4g09670;
DE EC=1.-.-.-;
GN OrderedLocusNames=At4g09670; ORFNames=F17A8.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 173-362.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (2.49 ANGSTROMS) OF 2-362, AND SUBUNIT.
RG Center for eukaryotic structural genomics (CESG);
RT "X-ray structure of gene product from Arabidopsis thaliana At4g09670.";
RL Submitted (JAN-2005) to the PDB data bank.
CC -!- SUBUNIT: Homodimer. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
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DR EMBL; AL049482; CAB39634.1; -; Genomic_DNA.
DR EMBL; AL161515; CAB78090.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82779.1; -; Genomic_DNA.
DR EMBL; BT002355; AAN86188.1; -; mRNA.
DR EMBL; AY045851; AAK76525.2; -; mRNA.
DR EMBL; AY085911; AAM63123.1; -; mRNA.
DR EMBL; AK220867; BAD94240.1; -; mRNA.
DR PIR; T04014; T04014.
DR RefSeq; NP_192705.1; NM_117035.4.
DR PDB; 1YDW; X-ray; 2.49 A; A/B=2-362.
DR PDB; 2Q4E; X-ray; 2.49 A; A/B=2-362.
DR PDBsum; 1YDW; -.
DR PDBsum; 2Q4E; -.
DR AlphaFoldDB; Q9SZ83; -.
DR SMR; Q9SZ83; -.
DR STRING; 3702.AT4G09670.1; -.
DR iPTMnet; Q9SZ83; -.
DR PaxDb; Q9SZ83; -.
DR PRIDE; Q9SZ83; -.
DR ProteomicsDB; 243006; -.
DR DNASU; 826553; -.
DR EnsemblPlants; AT4G09670.1; AT4G09670.1; AT4G09670.
DR GeneID; 826553; -.
DR Gramene; AT4G09670.1; AT4G09670.1; AT4G09670.
DR KEGG; ath:AT4G09670; -.
DR Araport; AT4G09670; -.
DR TAIR; locus:2118440; AT4G09670.
DR eggNOG; KOG2741; Eukaryota.
DR HOGENOM; CLU_023194_5_3_1; -.
DR InParanoid; Q9SZ83; -.
DR OMA; QWISITR; -.
DR OrthoDB; 943656at2759; -.
DR PhylomeDB; Q9SZ83; -.
DR EvolutionaryTrace; Q9SZ83; -.
DR PRO; PR:Q9SZ83; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SZ83; baseline and differential.
DR Genevisible; Q9SZ83; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Oxidoreductase; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..362
FT /note="Uncharacterized oxidoreductase At4g09670"
FT /id="PRO_0000091788"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CONFLICT 173
FT /note="I -> M (in Ref. 5; BAD94240)"
FT /evidence="ECO:0000305"
FT STRAND 7..13
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 18..27
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 31..37
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 41..50
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 58..62
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 63..68
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 74..77
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 81..83
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 84..92
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 93..95
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 97..100
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 105..107
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 108..119
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 120..122
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 125..127
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 131..133
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 135..137
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 138..142
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 143..145
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 147..150
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 152..163
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 166..171
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 173..175
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 183..187
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 189..199
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 200..202
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 206..210
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 222..230
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 232..234
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 236..264
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 273..281
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 288..293
FT /evidence="ECO:0007829|PDB:1YDW"
FT STRAND 296..301
FT /evidence="ECO:0007829|PDB:1YDW"
FT HELIX 306..314
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 322..324
FT /evidence="ECO:0007829|PDB:2Q4E"
FT HELIX 332..351
FT /evidence="ECO:0007829|PDB:1YDW"
FT TURN 352..354
FT /evidence="ECO:0007829|PDB:1YDW"
SQ SEQUENCE 362 AA; 39562 MW; EC2595BE6C53AACC CRC64;
MATETQIRIG VMGCADIARK VSRAIHLAPN ATISGVASRS LEKAKAFATA NNYPESTKIH
GSYESLLEDP EIDALYVPLP TSLHVEWAIK AAEKGKHILL EKPVAMNVTE FDKIVDACEA
NGVQIMDGTM WVHNPRTALL KEFLSDSERF GQLKTVQSCF SFAGDEDFLK NDIRVKPGLD
GLGALGDAGW YAIRATLLAN NFELPKTVTA FPGAVLNEAG VILSCGASLS WEDGRTATIY
CSFLANLTME ITAIGTKGTL RVHDFIIPYK ETEASFTTST KAWFNDLVTA WVSPPSEHTV
KTELPQEACM VREFARLVGE IKNNGAKPDG YWPSISRKTQ LVVDAVKESV DKNYQQISLS
GR
