ID   Y499_MYCTU              Reviewed;         291 AA.
AC   P9WKT9; L0T5J6; P64719; Q11164;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Uncharacterized protein Rv0499;
GN   OrderedLocusNames=Rv0499; ORFNames=MTCY20G9.25;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP43234.1; -; Genomic_DNA.
DR   PIR; F70745; F70745.
DR   RefSeq; NP_215013.1; NC_000962.3.
DR   RefSeq; WP_003402433.1; NZ_NVQJ01000002.1.
DR   AlphaFoldDB; P9WKT9; -.
DR   SMR; P9WKT9; -.
DR   STRING; 83332.Rv0499; -.
DR   PaxDb; P9WKT9; -.
DR   DNASU; 887243; -.
DR   GeneID; 45424461; -.
DR   GeneID; 887243; -.
DR   KEGG; mtu:Rv0499; -.
DR   TubercuList; Rv0499; -.
DR   eggNOG; COG2050; Bacteria.
DR   OMA; WFDEDHT; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR   Gene3D; 2.40.160.210; -; 1.
DR   InterPro; IPR042171; Acyl-CoA_hotdog.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF54637; SSF54637; 2.
DR   PROSITE; PS50146; DAGK; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..291
FT                   /note="Uncharacterized protein Rv0499"
FT                   /id="PRO_0000103703"
FT   DOMAIN          68..205
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00783"
SQ   SEQUENCE   291 AA;  30670 MW;  E7FDCF50D78E6198 CRC64;
     MNALFTTAMA LRPLDSDPGN PACRVFEGEL NEHWTIGPKV HGGAMVALCA NAARTAYGAA
     GQQPMRQPVA VSASFLWAPD PGTMRLVTSI RKRGRRISVA DVELTQGGRT AVHAVVTLGE
     PEHFLPGVDG SGGASGTAPL LSANPVVELM APEPPEGVVP IGPGHQLAGL VHLGEGCDVR
     PVLSTLRSAT DGRPPVIQLW ARPRGVAPDA LFALLCGDLS APVTFAVDRT GWAPTVALTA
     YLRALPADGW LRVLCTCVEI GQDWFDEDHI VVDRLGRIVV QTRQLAMVPA Q