ID   Y4FA_SINFN              Reviewed;         845 AA.
AC   P55439;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 129.
DE   RecName: Full=Probable chemoreceptor y4fA;
DE   AltName: Full=Methyl-accepting chemotaxis protein;
GN   OrderedLocusNames=NGR_a03800; ORFNames=y4fA;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Chemotactic-signal transducers respond to changes in the
CC       concentration of attractants and repellents in the environment,
CC       transduce a signal from the outside to the inside of the cell, and
CC       facilitate sensory adaptation through the variation of the level of
CC       methylation. Attractants increase the level of methylation while
CC       repellents decrease the level of methylation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91658.1; -; Genomic_DNA.
DR   RefSeq; NP_443846.1; NC_000914.2.
DR   RefSeq; WP_010875392.1; NC_000914.2.
DR   AlphaFoldDB; P55439; -.
DR   SMR; P55439; -.
DR   STRING; 394.NGR_a03800; -.
DR   PRIDE; P55439; -.
DR   EnsemblBacteria; AAB91658; AAB91658; NGR_a03800.
DR   KEGG; rhi:NGR_a03800; -.
DR   PATRIC; fig|394.7.peg.389; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG2972; Bacteria.
DR   HOGENOM; CLU_000445_64_0_5; -.
DR   OrthoDB; 429006at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Chemotaxis; Membrane; Methylation; Plasmid;
KW   Reference proteome; Repeat; Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..845
FT                   /note="Probable chemoreceptor y4fA"
FT                   /id="PRO_0000110569"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          451..502
FT                   /note="HAMP 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          530..582
FT                   /note="HAMP 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          587..816
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
SQ   SEQUENCE   845 AA;  89611 MW;  C140A50C0D864F7B CRC64;
     MGWVDRLLSR FKIRTKVMLL VLPFILSISA VGVTGMLASG LLQSRMAISN DVAASLRGFK
     DVYAAMIGFL DQTTEENRAL VFSKLDEQRA ALDAAGARLT PKAEGWAELE SASAALSAIN
     GRMDDLWALH ADEARLEAGI KEALGVISTS QADLLTAATA FDKSISTQED DAKEKLRDAQ
     RILSATSFVV ALRDAFAARK DDGEGYRAIA AAMGDLKIHQ KLLPIALPKK SKPLGKAFSA
     NVRALSALVD DKARPPENIE KILDVFAELK ALKEPLEAAA TAKMQHVSTT FEELDASVAK
     AGLVMQDTRH LTDAIYLTRI ALAEFMLDRS AEKQSTLAMH LAQCRNALFA LSSTAGDLGF
     AGEQSTKLAT SFDRIEQSAV ELVGATGKRT QQFQAAADEI DHIGEQISLF ADLQRSAAGR
     QSQDANRLSI GAMVLGVIIA LVSGAALVLT LKGPIGEITQ TMRNLAGGLL DTAVANRNRA
     DEIGEMARAL DVFKTNAKAR IALEQRSEQE RVAAHAERER NEAEKLRRDQ EIAFAVDALA
     DGLDAMAKGR LTSTIETPFA PALDKLRTDF NAAVAGLRQT LLDIRTTSSV IQGSGRQMAE
     GAKALSGRTE QQAASLEETA ASVDEIVATI RRAGDQAANA DNTVSKAKQD ADRSTVVVGN
     ATAAMGRIEA ASSHIGHIIE VIDDIAFQIN LLALNAGIEA ARAGEAGKGF AVVAQEVREL
     AQRSAGAARE IAALIGNSTA EVAKGAGLVS ETGAALLDIS KHILEISTQI EAIALSSREQ
     ASSIAEVNVA ITRLDQLTQS NAAMAEETQA ASWTLSGEAD YLMQLVDRFD LGENSGSASE
     TMKAA