ID   Y4LA_SINFN              Reviewed;         278 AA.
AC   P55541;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Uncharacterized short-chain type dehydrogenase/reductase y4lA;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=NGR_a02730; ORFNames=y4lA;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91754.1; -; Genomic_DNA.
DR   PIR; T10877; T10877.
DR   RefSeq; NP_443952.1; NC_000914.2.
DR   RefSeq; WP_010875298.1; NC_000914.2.
DR   AlphaFoldDB; P55541; -.
DR   SMR; P55541; -.
DR   STRING; 394.NGR_a02730; -.
DR   EnsemblBacteria; AAB91754; AAB91754; NGR_a02730.
DR   KEGG; rhi:NGR_a02730; -.
DR   PATRIC; fig|394.7.peg.291; -.
DR   eggNOG; COG1028; Bacteria.
DR   HOGENOM; CLU_010194_1_0_5; -.
DR   OMA; ITYNSRA; -.
DR   OrthoDB; 1356861at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Plasmid; Reference proteome.
FT   CHAIN           1..278
FT                   /note="Uncharacterized short-chain type
FT                   dehydrogenase/reductase y4lA"
FT                   /id="PRO_0000054887"
FT   ACT_SITE        159
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         146
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   278 AA;  28743 MW;  1D0105625BE9DF2B CRC64;
     MERFEGKVAV VTGAGAGIGK ACALAIAREG GRVVVADLDG SAAIACTAQI AAEAGNALAM
     AMDIADAQAV AALFETAERH FGGVDLLVNN ASAMHLTPRD RAILDLDLAV WDQTMATNLR
     GTLLCCRQAI PRMIARGGGA IVNMSSCQGL SGDTAQTSYA VSKAAMNMLS ASLATQYGHA
     QIRCNAVAPG LIMTERLLAK LDKCMQRHLS RHQLLPRVGH PEDVAALVAF LLSDDASFIT
     GQVVCIDGGM LAHMPTYADG GNSCAGRTAG DTAETARC