ID   Y4LH_SINFN              Reviewed;         192 AA.
AC   P55548;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Probable protein adenylyltransferase y4lH;
DE            EC=2.7.7.n1;
GN   OrderedLocusNames=NGR_a02670; ORFNames=y4lH;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Probable adenylyltransferase that mediates the addition of
CC       adenosine 5'-monophosphate (AMP) to specific residues of target
CC       proteins. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-
CC         tyrosyl-[protein]; Xref=Rhea:RHEA:54288, Rhea:RHEA-COMP:10136,
CC         Rhea:RHEA-COMP:13846, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:46858, ChEBI:CHEBI:83624; EC=2.7.7.n1;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-
CC         [protein] + diphosphate; Xref=Rhea:RHEA:54292, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:13847, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:138113; EC=2.7.7.n1;
CC   -!- SIMILARITY: Belongs to the fic family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91760.1; -; Genomic_DNA.
DR   RefSeq; NP_443958.1; NC_000914.2.
DR   RefSeq; WP_010875292.1; NC_000914.2.
DR   AlphaFoldDB; P55548; -.
DR   SMR; P55548; -.
DR   STRING; 394.NGR_a02670; -.
DR   EnsemblBacteria; AAB91760; AAB91760; NGR_a02670.
DR   KEGG; rhi:NGR_a02670; -.
DR   PATRIC; fig|394.7.peg.282; -.
DR   eggNOG; COG2184; Bacteria.
DR   HOGENOM; CLU_080158_0_2_5; -.
DR   OMA; FCHFEYI; -.
DR   OrthoDB; 1232677at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3290.10; -; 1.
DR   InterPro; IPR003812; Fido.
DR   InterPro; IPR036597; Fido-like_dom_sf.
DR   Pfam; PF02661; Fic; 1.
DR   SUPFAM; SSF140931; SSF140931; 1.
DR   PROSITE; PS51459; FIDO; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Nucleotidyltransferase; Plasmid;
KW   Reference proteome; Transferase.
FT   CHAIN           1..192
FT                   /note="Probable protein adenylyltransferase y4lH"
FT                   /id="PRO_0000200902"
FT   DOMAIN          52..190
FT                   /note="Fido"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00791"
FT   BINDING         82..83
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         139..141
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   192 AA;  22438 MW;  CA883199329E0474 CRC64;
     MVRYNAVEDP LCYPGTHVLR NRANIPDQNE LDEFEQLMFD SRAREALPDG DLDFAHYRAL
     HRHFFQDVYE WAGQTRIIRT GKGENWFCYP EYIEREANRL FAELAARDHL ARTESKEAFA
     KGASWFLAEI NAIHPFREGN GRTQLVFLTM LTRYAGYELD ESKLEPKRFL DAMIRSFSGD
     LAPLAAEIRR MI