ID   Y4PA_SINFN              Reviewed;         609 AA.
AC   P55610;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Putative transcriptional regulatory protein y4pA;
GN   OrderedLocusNames=NGR_a02110; ORFNames=y4pA;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Probable transcriptional regulator that acts in conjunction
CC       with sigma-54.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00090; AAB91811.1; -; Genomic_DNA.
DR   RefSeq; NP_444014.1; NC_000914.2.
DR   RefSeq; WP_010875238.1; NC_000914.2.
DR   AlphaFoldDB; P55610; -.
DR   SMR; P55610; -.
DR   STRING; 394.NGR_a02110; -.
DR   PRIDE; P55610; -.
DR   EnsemblBacteria; AAB91811; AAB91811; NGR_a02110.
DR   KEGG; rhi:NGR_a02110; -.
DR   PATRIC; fig|394.7.peg.222; -.
DR   eggNOG; COG2204; Bacteria.
DR   eggNOG; COG5564; Bacteria.
DR   HOGENOM; CLU_000445_122_0_5; -.
DR   OMA; EWILDAL; -.
DR   OrthoDB; 123059at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR009215; TIM-br_IGPS-like.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF09370; PEP_hydrolase; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   PRINTS; PR01590; HTHFIS.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   ATP-binding; DNA-binding; Nucleotide-binding; Plasmid; Reference proteome;
KW   Transcription; Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..609
FT                   /note="Putative transcriptional regulatory protein y4pA"
FT                   /id="PRO_0000081402"
FT   DOMAIN          313..533
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   DNA_BIND        578..597
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   BINDING         395..404
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ   SEQUENCE   609 AA;  66700 MW;  8CC727E67D508F36 CRC64;
     MADPIVHPGV HRPEFSAPLH ARAEIIATLR AALGKPNTTL VGAAIGTGMA AQAASRGGAD
     FILALNAGRL RSMGAPSIFS LLALRKSNDF VLDFAQSEIL PFVKVPVFFG ASAFDPRCSI
     EAELERIADA GFGAIVNFPT SIFLDGRFRA DIEGAGLGFQ RELEMLRAAQ KRNMATLAYV
     RTVAEAQQAA TAGVDIINLN LGWNVGGTVG SRTELSLRQA AEYAKIIFRQ IRAISEDTLC
     VLEGGPIVSP DQMYEVSALS KADGYIGGST IDRVPLEASM EQITSAFKSV GTLQKRIDEL
     ERQLEHVQRE YSIVGRSPSI QQIKQRIEKL AASSLPVMIT GQAGTGKKLL ARGIHEAARR
     SGSKLISSED ASGESLFGFA PSEGGRKVLG LLQYHPKATL LIESVECLCV DAQERLIEVI
     ETGAYRRLGD NERGRFEGRL ILASTRPLPE LGSSGQLIPA LESRLAPGHV FLPPLCDRLE
     DLPLLAEHFL QALRKDRRSR KLSVDHSAYR VLMTYGWPEN IRELRSVLET AAIRCEGDWI
     KSEHLPPLGD ANADAPHPHP GEEREWILDA LQRHRFRRGE AARYLGISRK TLYNKMRVYG
     LPLQPRERS